[HTML][HTML] The multifaceted anti-cancer effects of BRAF-inhibitors

L Croce, F Coperchini, F Magri, L Chiovato… - Oncotarget, 2019 - ncbi.nlm.nih.gov
The BRAF gene is commonly involved in normal processes of cell growth and differentiation.
The BRAF (V600E) mutation is found in several human cancer, causing an increase of cell …

[HTML][HTML] The immune landscape of papillary thyroid cancer in the context of autoimmune thyroiditis

F Pani, P Caria, Y Yasuda, M Makoto, S Mariotti… - Cancers, 2022 - mdpi.com
Simple Summary The association between papillary thyroid cancer and Hashimoto's
thyroiditis went through a long-standing human debate recently elucidated by the …

[HTML][HTML] Identification of ferroptosis genes in immune infiltration and prognosis in thyroid papillary carcinoma using network analysis

R Lin, CE Fogarty, B Ma, H Li, G Ni, X Liu, J Yuan… - BMC genomics, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the most common thyroid cancer. While
many patients survive, a portion of PTC cases display high aggressiveness and even …

[HTML][HTML] Seven genes associated with lymphatic metastasis in thyroid cancer that is linked to tumor immune cell infiltration

L Wu, Y Zhou, Y Guan, R Xiao, J Cai, W Chen… - Frontiers in …, 2022 - frontiersin.org
Objective Since there are few studies exploring genes associated with lymphatic metastasis
of thyroid carcinoma (THCA), this study was conducted to explore genes associated with …

[HTML][HTML] Poorly differentiated and anaplastic thyroid cancer: Insights into genomics, microenvironment and new drugs

A Prete, A Matrone, C Gambale, L Torregrossa… - Cancers, 2021 - mdpi.com
Simple Summary In the last decades, many researchers produced promising data
concerning genetics and tumor microenvironment of poorly differentiated thyroid cancer …

[HTML][HTML] TPO as an indicator of lymph node metastasis and recurrence in papillary thyroid carcinoma

X Li, R Cheng - Scientific Reports, 2023 - nature.com
The objective of this study was to investigate the expression of thyroid peroxidase (TPO) in
papillary thyroid carcinoma (PTC) and to preliminarily investigate its value as a marker of …

[HTML][HTML] Anti-cancer serca inhibitors targeting sorafenib-resistant human papillary thyroid carcinoma

HS Chang, Y Kim, SY Lee, HJ Yun, HJ Chang… - International Journal of …, 2023 - mdpi.com
Thyroid cancer is generally curable and, in many cases, can be completely treated, although
it can sometimes recur after cancer therapy. Papillary thyroid cancer (PTC) is known as one …

AHNAK2 is a novel prognostic marker and correlates with immune infiltration in papillary thyroid cancer: Evidence from integrated analysis

L Zheng, S Li, X Zheng, R Guo, W Qu - International Immunopharmacology, 2021 - Elsevier
Papillary thyroid cancer (PTC) is the most prevalent endocrine tumor, and its incidence is
still increasing. The mechanisms of PTC dedifferentiation and malignant progression remain …

TREM1 fosters an immunosuppressive tumor microenvironment in papillary thyroid cancer

Y Zhao, C Zhang, Y Zhu, X Ding… - Endocrine-Related …, 2022 - erc.bioscientifica.com
The immunosuppressive microenvironment is associated with poor prognosis in papillary
thyroid cancer (PTC); however, the molecular mechanisms involved are unknown. Among …

[HTML][HTML] Identification of potential LncRNAs as papillary thyroid carcinoma biomarkers based on integrated bioinformatics analysis using TCGA and RNA sequencing …

JL Feng, WJ Zheng, L Xu, QY Zhou, J Chen - Scientific Reports, 2023 - nature.com
The roles and mechanisms of long non-coding RNAs (lncRNAs) in papillary thyroid cancer
(PTC) remain elusive. We obtained RNA sequencing (RNA-seq) data of surgical PTC …