The increased metabolic activity of the heart as a pump involves a high demand of
mitochondrial adenosine triphosphate (ATP) production for its mechanical and electrical …

Cardiovascular diseases (CVD) account for the largest bulk of deaths worldwide, posing a
massive burden on societies and the global healthcare system. Besides, the incidence and …

Heart failure is a risk factor for adverse events such as sudden cardiac arrest, liver and
kidney failure and death. The gut microbiota and its metabolites are directly linked to the …

Metabolic reprogramming of vascular smooth muscle cell (VSMC) plays a critical role in the
pathogenesis of thoracic aortic dissection (TAD). Previous researches have mainly focused …

As a terminal stage of various cardiovascular diseases, heart failure is of great concern due
to its high mortality rate and limited treatment options. Researchers are currently focusing …

Heart failure (HF) is a complex and multifactorial disease that affects millions of people
worldwide. It is characterized by metabolic disturbances of substrates such as glucose, fatty …

Dysregulated amino acid metabolism in heart failure: role of... : Current Opinion in Clinical
Nutrition & Metabolic Care Dysregulated amino acid metabolism in heart failure: role of gut …

Background The exact mechanism of atrial fibrillation (AF)-induced heart failure (HF)
remains unclear. Proteomics and metabolomics were integrated to in this study, as to …

Several observational studies have indicated an association between high serum levels of
branched-chain amino acids (BCAAs) and an increased risk of cardiovascular disease …

Heart disease is the leading cause of mortality in developed countries. The associated
pathology is characterized by a loss of cardiomyocytes that leads, eventually, to heart failure …