Pancreatic cancer has a poor prognosis. Lack of diagnostic markers prevents its early
diagnosis and treatment. Pathogenic germline variation in BRCA1 and BRCA2 (BRCA) is …

Germline variants occurring in BRCA1 and BRCA2 give rise to hereditary breast and ovarian
cancer (HBOC) syndrome, predisposing to breast, ovarian, fallopian tube, and peritoneal …

Prostate cancer (PCa) is a tumor with a great heterogeneity, both at a molecular and clinical
level. Despite its global good prognosis, cases can vary from indolent to lethal metastatic …

The role of molecular imaging in initial evaluation of men with presumed or established
diagnosis of prostate cancer and work up of biochemical recurrence and metastatic disease …

Prostate cancer (PCa) is a common malignant tumor with increasing incidence and high
heterogeneity among males worldwide. In the era of big data and artificial intelligence, the …

Hereditary cancers mostly affect the adolescent and young adult population (AYA) at
reproductive age. Mutations in BReast CAncer (BRCA) genes are responsible for the …

Background and objective MLF1IP has been correlated with the progression and prognosis
of a few tumors. However, the role of MLF1IP in colorectal cancer remains unclear. Here, we …

A BRCA2 prostate cancer cluster region (PCCR) was recently proposed (c. 7914 to 3′)
wherein pathogenic variants (PVs) are associated with higher prostate cancer (PCa) risk …

Objective: As prostate cancer (PrC) shows a BRCA mutation rate as high as 30%, it
becomes crucial to find the optimal selection criteria for genetic testing. The primary …

Background: Prostate cancer (PCa) is a kind of malignant tumor with high incidence among
males worldwide. The identification of novel biomarker signatures is therefore of clinical …