Roles and crosstalks of macrophages in diabetic nephropathy

HD Li, YK You, BY Shao, WF Wu, YF Wang… - Frontiers in …, 2022 - frontiersin.org
Diabetic nephropathy (DN) is the most common chronic kidney disease. Accumulation of
glucose and metabolites activates resident macrophages in kidneys. Resident macrophages …

Chronic kidney disease as a systemic inflammatory syndrome: update on mechanisms involved and potential treatment

F Tinti, S Lai, A Noce, S Rotondi, G Marrone… - Life, 2021 - mdpi.com
Chronic kidney disease (CKD) is characterized by manifestations and symptoms involving
systemic organs and apparatus, associated with elevated cardiovascular morbidity and …

[PDF][PDF] Expanded umbilical cord mesenchymal stem cells (UC-MSCs) as a therapeutic strategy in managing critically ill COVID-19 patients: the case for compassionate …

S Atluri, L Manchikanti, JA Hirsch - Pain physician, 2020 - sah.org.ar
2. Institute appropriate safeguards to avoid negative consequences from unscrupulous
actors. 3. With proper informed consent from patients or proxy when necessary, and subject …

Circular RNA in renal diseases

J Jin, H Sun, C Shi, H Yang, Y Wu, W Li… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …

Proficient novel biomarkers guide early detection of acute kidney injury: a review

S Jana, P Mitra, S Roy - Diseases, 2022 - mdpi.com
The definition of acute kidney injury (AKI), despite improvements in criteria, continues to be
based on the level of serum creatinine and urinary output that do not specifically indicate …

The immune system as a target for therapy of SARS-CoV-2: a systematic review of the current immunotherapies for COVID-19

AH Mansourabadi, M Sadeghalvad… - Life sciences, 2020 - Elsevier
Aims The immune response is essential for the control and resolution of viral infections.
Following the outbreak of novel coronavirus disease (COVID-19), several immunotherapies …

Engineering ultrasmall ferroptosis‐targeting and reactive oxygen/nitrogen species‐scavenging nanozyme for alleviating acute kidney injury

K Wang, Y Zhang, W Mao, W Feng, S Lu… - Advanced Functional …, 2022 - Wiley Online Library
Acute kidney injury (AKI) is a serious renal dysfunction syndromes, which predominantly
correlates with the excess production of endogenous reactive oxygen/nitrogen species …

Long-term effects of severe burns on the kidneys: research advances and potential therapeutic approaches

G Yang, L Tan, H Yao, Z Xiong, J Wu… - Journal of Inflammation …, 2023 - Taylor & Francis
Burns are a seriously underestimated form of trauma that not only damage the skin system
but also cause various complications, such as acute kidney injury (AKI). Recent clinical …

FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis

X Zhu, C Qiu, Y Wang, Y Jiang… - Proceedings of the …, 2022 - National Acad Sciences
Angiogenesis contributes fundamentally to embryonic development, tissue homeostasis,
and wound healing. Basic fibroblast growth factor (FGF2) is recognized as the first …

Kidney organoids and tubuloids

FA Yousef Yengej, J Jansen, MB Rookmaaker… - Cells, 2020 - mdpi.com
In the past five years, pluripotent stem cell (PSC)-derived kidney organoids and adult stem
or progenitor cell (ASC)-based kidney tubuloids have emerged as advanced in vitro models …