Real-world experience with subcutaneous infliximab: broadening treatment strategies for inflammatory bowel disease

PJ Smith, M Fumery, RW Leong, K Novak… - Expert Review of …, 2023 - Taylor & Francis
Introduction The first subcutaneous (SC) formulation of infliximab (IFX), CT‑P13 SC, has
been approved in Europe and Australia, including for the treatment of inflammatory bowel …

Switching from intravenous to subcutaneous infliximab and vedolizumab in patients with inflammatory bowel disease: impact on trough levels, day hospital visits, and …

J Harno-Tasihin, L Siregar, M Paajanen… - Scandinavian Journal …, 2024 - Taylor & Francis
Abstract Objective Subcutaneous (SC) infliximab (IFX) and vedolizumab (VDZ) have recently
become available. We aimed to examine the impact of switching from intravenous (IV) to SC …

Inflammatory bowel disease patients' acceptance for switching from intravenous infliximab or vedolizumab to subcutaneous formulation: The Nancy Experience

C Remy, B Caron, C Gouynou, V Haghnejad… - Journal of Clinical …, 2022 - mdpi.com
Background: Subcutaneous infliximab and vedolizumab formulations have been developed
for maintenance therapy in inflammatory bowel disease. The objective of this study was to …

Benefits of Biosimilars in the Management of Patients with Inflammatory Bowel Disease: An International Survey

F D'Amico, L Peyrin-Biroulet, S Danese - Journal of Clinical Medicine, 2024 - mdpi.com
Background/Objectives: The development of biosimilar drugs has revolutionized the
management of patients with inflammatory bowel diseases (IBD), significantly reducing …

Long‐term effectiveness and acceptability of switching from intravenous to subcutaneous infliximab in patients with inflammatory bowel disease treated with intensified …

A Buisson, M Nachury, M Bazoge… - Alimentary …, 2024 - Wiley Online Library
Background The long‐term risk of relapse after switching from intravenous (IV) to
subcutaneous (SC) infliximab remains unknown in inflammatory bowel disease (IBD). Aims …

[HTML][HTML] Switching from intravenous to subcutaneous infliximab maintenance therapy in inflammatory bowel disease: Post hoc longitudinal analysis of a randomized …

S Schreiber, G D'Haens, F Cummings, PM Irving… - Digestive and Liver …, 2024 - Elsevier
Background Pharmacokinetic non-inferiority of subcutaneous (SC) to intravenous (IV) CT-
P13 maintenance therapy was demonstrated in a randomized trial (NCT02883452). This …

Subcutaneous Infliximab (CT-P13 SC) as Maintenance Therapy for Inflammatory Bowel Disease: Two Randomized Phase 3 Trials

SB Hanauer, BE Sands, S Schreiber, S Danese… - Gastroenterology, 2024 - Elsevier
Abstract Background and Aims CT-P13 subcutaneous (SC), an SC formulation of the
intravenous (IV) infliximab biosimilar CT-P13 IV, creates a unique exposure profile. We …