In addition to the burden of a life-threatening diagnosis, cancer patients are struggling with
adverse side-effects from cancer treatment. Chemotherapy has been linked to an array of …

Natural products are of great surge in the identification of chemopreventive agents and
biologically active molecules for the development of new promising therapeutic agents …

Pediatric cancer and its treatment are associated with increased risk for acute and chronic
cognitive impairments. Neuroimaging studies indicate a common biologic pathway of …

Purpose Little is known regarding long-term neurocognitive outcomes in osteosarcoma and
Ewing sarcoma (EWS) survivors despite potential risk factors. We evaluated associations …

Background Cancer survival comes at a price: pediatric cancer survivors bear a high risk for
a wide range of cognitive difficulties. Therefore, interventions targeting these difficulties are …

Objective Childhood cancer and cancer‐related treatments disrupt brain development and
maturation, placing survivors at risk for cognitive late effects. Given that assessment tools …

Cognitive impairment is frequent in pediatric cancer, and behavioral and psychological
disturbances often also affect children who have survived cancer problems. Furthermore …

With the increase of survival rates of pediatric cancer patients, the number of children facing
potential cognitive sequelae has grown. Previous adult studies suggest that white matter …

In recent years, and particularly associated with the increase of cancer patients' life
expectancy, the occurrence of cancer treatment sequelae, including cognitive impairments …

Methotrexate (MTX) is a folic acid antagonist and widely used for acute lymphoblastic
leukemia (ALL) in children. MTX is associated with acute and chronic neurotoxicity during …