Lysine Methyltransferase 9 (KMT9) Is an Actionable Target in Muscle-Invasive Bladder Cancer

S Totonji, A Ramos-Triguero, D Willmann, M Sum… - Cancers, 2024 - mdpi.com
Simple Summary The recently identified lysine methyltransferase (KMT) 9 regulates the
growth of different types of cancer. While KMT9 was shown to be overexpressed in muscle …

Visualization of Cellular Membranes in 2D and 3D Conditions Using a New Fluorescent Dithienothiophene S,S-Dioxide Derivative

A Rzewnicka, J Krysiak, R Pawłowska… - International Journal of …, 2023 - mdpi.com
Cellular membranes play a key role in cell communication with the extracellular environment
and neighboring cells. Any changes, including their composition, packing, physicochemical …

High-throughput formulation of reproducible 3D cancer microenvironments for drug testing in myelogenous leukemia

M Rudzinska-Radecka, L Turos-Korgul, D Mukherjee… - bioRxiv, 2024 - biorxiv.org
Targeting cancer microenvironment is currently one of the major directions in drug
development and preclinical studies in leukemia. Despite the variety of available chronic …

[HTML][HTML] Progress in patient-derived liver cancer cell models: a step forward for precision medicine: Patient-derived cell models for precision medicine of liver cancers

Z Zhang, L Hui - Acta Biochimica et Biophysica Sinica, 2023 - ncbi.nlm.nih.gov
The development of effective precision treatments for liver cancers has been hindered by the
scarcity of preclinical models that accurately reflect the heterogeneity of this disease. Recent …

Advancing Mixed Reality Digital Twins Through 3D Reconstruction of Fresh Produce

M Nair, RE Fernandez - IEEE Access, 2024 - ieeexplore.ieee.org
Access to safe and secure food is an essential human requirement for a sustainable world.
Ensuring the safety of fresh food products necessitates accurate analytical techniques. This …

DCM-Spheroid Morphs Express PADs and Citrullinated Cytoskeletal Proteins

A Sadiq, J Fert-Bober - Journal of Histochemistry & …, 2024 - journals.sagepub.com
During investigating the role of peptidylarginine deiminase (PAD) enzymes in dilated
cardiomyopathy (DCM), we observed unique spheroid formation in DCM-myofibroblasts that …

Organoid co‐culture models of the tumor microenvironment promote precision medicine

Z Gu, Q Wu, B Shang, K Zhang, W Zhang - Cancer Innovation, 2024 - Wiley Online Library
In recent years, the three‐dimensional (3D) culture system has emerged as a promising
preclinical model for tumor research owing to its ability to replicate the tissue structure and …

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NK Incorporating, B Arjmand… - Skin Stem Cells …, 2024 - books.google.com
Natural killer (NK) cells are a part of a sophisticated immune system that is necessary for the
skin because it is a crucial organ that is continually exposed to environmental influences …

[PDF][PDF] Lysine Methyltransferase 9 (KMT9) Is an Actionable Target in Muscle-Invasive Bladder Cancer. Cancers 2024, 16, 1532

S Totonji, A Ramos-Triguero, D Willmann, M Sum… - 2024 - e-helvetica.nb.admin.ch
Novel treatment modalities are imperative for the challenging management of
muscleinvasive and metastatic BC to improve patient survival rates. The recently identified …

[PDF][PDF] COLTURE 3D COME MODELLO PER STUDIARE IL MICROAMBIENTE TUMORALE DEL MESOTELIOMA MALIGNO

A Lamarca - 2024 - iris.unisr.it
ABSTRACT Malignant Pleural Mesothelioma is a very aggressive cancer arising from
pleural mesothelial cells exposed to asbestos. MPM poses a significant clinical challenge …