Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …

Metformin is one of the most used diabetic drugs for the management of type II diabetes
mellitus (DM) in the world. Increased numbers of epidemiological and clinical studies have …

Background Glioblastoma multiforme (GBM) is characterized by lethal aggressiveness and
patients with GBM are in urgent need for new therapeutic avenues to improve quality of life …

If the genome defines the program for the operations of a cell, signaling networks execute it.
These cascades of chemical, cell-biological, structural, and trafficking events span …

Glioblastomas (GBs) are one of the most aggressive and invasive intracranial cancers.
Recently, it has been postulated that, among other factors, the hedgehog (HH) pathway may …

MicroRNAs (miRNAs) are small, non-coding, endogenous RNA molecules that function in
gene silencing by post-transcriptional regulation of gene expression. The dysregulation of …

Glioblastoma (GBM) is human's most prevalent and severe brain cancer. Epigenetic
regulators, micro (mi) RNAs, significantly impact cellular health and disease because of their …

The cellular dispersion and therapeutic control of glioblastoma, the most aggressive type of
primary brain cancer, depends critically on the migration patterns after surgery and …

MicroRNAs play an important role in tumor development and progression. Tumor growth is
closely associated with glucose metabolism. Specifically, tumor cells produce energy (ATP) …

OBJECTIVE The authors' goal was to use a multicenter, observational cohort study to
determine whether supramarginal resection (SMR) of FLAIR-hyperintense tumor beyond the …