Creatine was previously shown to produce an antidepressant-like effect in the tail
suspension test through a modulation of the dopaminergic system. In this study, the …

Creatine is a nutritional compound that potentially influences cognitive processing and
neuroprotection. Recent evidence has demonstrated that similar to neurotransmitters …

The antidepressant-like activity of creatine in the tail suspension test (TST) was
demonstrated previously by our group. In this study we investigated the involvement of the …

Mood disorders, including major depressive disorder and bipolar disorder, have a profound
impact on more than 300 million people worldwide. It has been demonstrated mood …

Cannabis has shown therapeutic potential in mood and anxiety-related pathologies.
However, the two primary constituents of cannabis, cannabidiol (CBD) and Δ-9 …

Background Posttraumatic stress disorder (PTSD) is a psychiatric condition characterized by
a prolonged stress response to potentially life-threatening events long after the event has …

Creatine's effects on brain energy metabolism raise the possibility of developing a new
therapeutic strategy in depression focusing on the treatment of metabolic hypoactive brain …

Selective serotonin reuptake inhibitors, such as fluoxetine (Prozac), are commonly
prescribed pharmacotherapies for anxiety. Fluoxetine may be a useful adjunct because it …

Approximately 20% of adults in the US will experience an affective disorder during their life.
While it is well established that serotonin (5-HT) is a crucial factor in mood, impaired cellular …

Creatine is an antioxidant, neuromodulator and key regulator of energy metabolism shown
to improve depressive symptoms in humans and animals, especially in females. To better …