[HTML][HTML] Carcinoid syndrome: preclinical models and future therapeutic strategies

G Vitale, S Carra, Y Alessi, F Campolo… - International Journal of …, 2023 - mdpi.com
Carcinoid syndrome represents a debilitating paraneoplastic disease, caused by the
secretion of several substances, occurring in about 10–40% of patients with well …

A luminescent sensor for investigating serotonin metabolism in neuroendocrine cancer

DH Tow, CHF Chan, JR Howe, PH Ear - Surgery, 2024 - Elsevier
Background Serotonin is emerging as a promising therapeutic target in tryptophan
hydroxylase 1–positive tumors, but further mechanistic studies are needed to effectively …

Updates in neuroendocrine neoplasms: from mechanisms to the clinic

S Fodil-Cherif, R Desailloud, T Brue - Annales d'Endocrinologie, 2023 - Elsevier
Scientific advances constantly improve our understanding of the mechanisms underlying
tumorigenesis, allowing us now to analyze cancer in a more precise manner and to identify …

The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes

Z Ye, Q Li, Y Hu, H Hu, J Xu, M Guo, W Zhang, X Lou… - Cancer Letters, 2024 - Elsevier
Cancer-associated fibroblasts (CAFs) play an important role in a variety of cancers.
However, the role of tumor stroma in nonfunctional pancreatic neuroendocrine tumors (NF …

胰腺神经内分泌肿瘤微环境的形成机制及免疫/靶向治疗研究进展.

杨佳妮, 张海蓉 - Journal of Clinical Hepatology/Linchuang …, 2023 - search.ebscohost.com
胰腺神经内分泌肿瘤微环境是由肿瘤细胞, 免疫/免疫抑制细胞和细胞外基质成分等共同构建的
促癌微环境, 以免疫抑制为突出特征, 不仅可以抑制抗肿瘤免疫反应, 促进血管新生导致肿瘤细胞 …

Research advances in the mechanism of tumor microenvironment and targeted therapy for pancreatic neuroendocrine tumor

H ZHANG - 临床肝胆病杂志, 2023 - lcgdbzz.org
The tumor microenvironment of pancreatic neuroendocrine tumor is a tumor-promoting
microenvironment composed of tumor cells, immune/immunosuppressive cells, and …

[HTML][HTML] NOUVEAUTES EN ONCO-ENDOCRINOLOGIE: DES MECANISMES A LA CLINIQUE

S Fodil-Cherif, CHU de Montpellier - sfendocrino.org
Les avancées scientifiques ne cessent d'améliorer notre compréhension des mécanismes
tumoraux, nous permettant désormais d'analyser les pathologies tumorales de manière de …