Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives

D Li, Y Rui, S Guo, F Luan, R Liu, N Zeng - Life sciences, 2021 - Elsevier
Ferulic acid, a kind of phenolic substance widely existing in plants, is an important active
component of many traditional Chinese medicines. So far, it has been proved that ferulic …

[HTML][HTML] Hallmarks of health

C López-Otín, G Kroemer - Cell, 2021 - cell.com
Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

[HTML][HTML] Epithelial-mesenchymal transition (EMT): the type-2 EMT in wound healing, tissue regeneration and organ fibrosis

GD Marconi, L Fonticoli, TS Rajan, SD Pierdomenico… - Cells, 2021 - mdpi.com
The epithelial–mesenchymal transition (EMT) is an essential event during cell development,
in which epithelial cells acquire mesenchymal fibroblast-like features including reduced …

Autophagy in liver diseases: a review

H Qian, X Chao, J Williams, S Fulte, T Li, L Yang… - Molecular aspects of …, 2021 - Elsevier
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …

Generation of functionally distinct T-cell populations by altering the viscoelasticity of their extracellular matrix

K Adu-Berchie, Y Liu, DKY Zhang… - Nature biomedical …, 2023 - nature.com
The efficacy of adoptive T-cell therapies largely depends on the generation of T-cell
populations that provide rapid effector function and long-term protective immunity. Yet it is …

Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors

S Francque, G Szabo, MF Abdelmalek… - Nature reviews …, 2021 - nature.com
The increasing epidemic of obesity worldwide is linked to serious health effects, including
increased prevalence of type 2 diabetes mellitus, cardiovascular disease and nonalcoholic …

[HTML][HTML] Fibrosis in chronic kidney disease: pathogenesis and consequences

S Panizo, L Martínez-Arias, C Alonso-Montes… - International journal of …, 2021 - mdpi.com
Fibrosis is a process characterized by an excessive accumulation of the extracellular matrix
as a response to different types of tissue injuries, which leads to organ dysfunction. The …

Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies

I Lurje, NT Gaisa, R Weiskirchen, F Tacke - Molecular Aspects of Medicine, 2023 - Elsevier
Fibrosis, or tissue scarring, develops as a pathological deviation from the physiological
wound healing response and can occur in various organs such as the heart, lung, liver …

Liquid bandage harvests robust adhesive, hemostatic, and antibacterial performances as a first‐aid tissue adhesive

Y Ma, J Yao, Q Liu, T Han, J Zhao, X Ma… - Advanced Functional …, 2020 - Wiley Online Library
Massive bleeding and wound infection after tissue trauma are the major dangerous factors
of casualties in disasters; hence, first‐aid supplies that can greatly achieve wound closure …

PPAR-γ signaling in nonalcoholic fatty liver disease: Pathogenesis and therapeutic targets

H Chen, H Tan, J Wan, Y Zeng, J Wang… - Pharmacology & …, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), currently the leading cause of global chronic liver
disease, has emerged as a major public health problem, more efficient therapeutics of which …