Targeted drug delivery with polymers and magnetic nanoparticles: covalent and noncovalent approaches, release control, and clinical studies
K Ulbrich, K Hola, V Subr, A Bakandritsos… - Chemical …, 2016 - ACS Publications
Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …
personalized medicine. This review covers the principles, advantages, and drawbacks of …
Self‐assembly of peptide amphiphiles: From molecules to nanostructures to biomaterials
Peptide amphiphiles are a class of molecules that combine the structural features of
amphiphilic surfactants with the functions of bioactive peptides and are known to assemble …
amphiphilic surfactants with the functions of bioactive peptides and are known to assemble …
Factors affecting the clearance and biodistribution of polymeric nanoparticles
F Alexis, E Pridgen, LK Molnar… - Molecular …, 2008 - ACS Publications
Nanoparticle (NP) drug delivery systems (5− 250 nm) have the potential to improve current
disease therapies because of their ability to overcome multiple biological barriers and …
disease therapies because of their ability to overcome multiple biological barriers and …
Serum ferritin: past, present and future
W Wang, MA Knovich, LG Coffman, FM Torti… - Biochimica et Biophysica …, 2010 - Elsevier
BACKGROUND: Serum ferritin was discovered in the 1930s, and was developed as a
clinical test in the 1970s. Many diseases are associated with iron overload or iron deficiency …
clinical test in the 1970s. Many diseases are associated with iron overload or iron deficiency …
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead
WH Goodson III, L Lowe, DO Carpenter… - …, 2015 - academic.oup.com
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide,
but credible estimates from the World Health Organization and the International Agency for …
but credible estimates from the World Health Organization and the International Agency for …
Advances in polymeric micelles for drug delivery and tumor targeting
A plethora of formulation techniques have been reported in the literature for targeting drugs
to specific sites. Polymeric micelles (PMs) can be targeted to tumor sites by passive as well …
to specific sites. Polymeric micelles (PMs) can be targeted to tumor sites by passive as well …
The role of signaling pathways in the development and treatment of hepatocellular carcinoma
S Whittaker, R Marais, AX Zhu - Oncogene, 2010 - nature.com
Hepatocellular carcinoma (HCC) is a highly prevalent, treatment-resistant malignancy with a
multifaceted molecular pathogenesis. Current evidence indicates that during …
multifaceted molecular pathogenesis. Current evidence indicates that during …
Nanotechnology in cancer drug delivery and selective targeting
KB Sutradhar, ML Amin - International scholarly research …, 2014 - Wiley Online Library
Nanoparticles are rapidly being developed and trialed to overcome several limitations of
traditional drug delivery systems and are coming up as a distinct therapeutics for cancer …
traditional drug delivery systems and are coming up as a distinct therapeutics for cancer …
STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells
Y Liu, F Luo, B Wang, H Li, Y Xu, X Liu, L Shi, X Lu… - Cancer letters, 2016 - Elsevier
Although microRNA (miRNA) enclosed in exosomes can mediate intercellular
communication, the roles of exosomal miRNA and angiogenesis in lung cancer remain …
communication, the roles of exosomal miRNA and angiogenesis in lung cancer remain …
Friends or foes—bipolar effects of the tumour stroma in cancer
MM Mueller, NE Fusenig - Nature Reviews Cancer, 2004 - nature.com
The restricted view of tumour progression as a multistep process defined by the
accumulation of mutations in cancer cells has largely ignored the substantial contribution of …
accumulation of mutations in cancer cells has largely ignored the substantial contribution of …