Human infections caused by the opportunist pathogens Burkholderia cepacia complex and
Pseudomonas aeruginosa are of particular concern due to their severity, their multiple …

The genus Burkholderia includes a wide range of Gram-negative bacterial species some of
which are pathogenic to humans and other vertebrates. The most pathogenic species are …

Increasing antimicrobial resistance due to misuse and overuse of antimicrobials, as well as
a lack of new and innovative antibiotics in development has become an alarming global …

Cystic fibrosis (CF) patients are at particular risk of infection by microorganisms that are
resistant to several antibiotics. About 3% of CF patients are colonized by Burkholderia …

Burkholderia are a group of Gram-negative bacteria that can cause a variety of diseases in
at-risk populations. B. pseudomallei and B. mallei, the etiological agents of melioidosis and …

The Burkholderia cepacia complex comprises environmental and clinical Gram-negative
bacteria that infect particularly debilitated people, such as those with cystic fibrosis. Their …

Infections by the Burkholderia cepacia complex (Bcc) remain seriously life threatening to
cystic fibrosis (CF) patients, and no effective eradication is available. A vaccine to protect …

Abstract The Burkholderia cepacia complex (Bcc) is a group of closely related bacterial
species that emerged in the 1980s as the etiological agents of severe and often lethal …

Burkholderia pseudomallei is an infectious bacterium of clinical and biodefense concern,
and is the causative agent of melioidosis. The mortality rate can reach up to 50% and affects …

Bacteria of the Burkholderia cepacia complex (Bcc) remain an important cause of morbidity
and mortality among patients suffering from cystic fibrosis. Eradication of these pathogens by …