A review on recent advances in nitrogen-containing molecules and their biological applications

N Kerru, L Gummidi, S Maddila, KK Gangu… - Molecules, 2020 - mdpi.com
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable
source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by …

[HTML][HTML] Pyrazole and pyrazoline derivatives as antimalarial agents: A key review

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2023 - Elsevier
Malaria poses a severe public health risk and a significant economic burden in disease-
endemic countries. One of the most severe issues in malaria control is the development of …

Biologically active pyrazole derivatives

A Ansari, A Ali, M Asif - New Journal of Chemistry, 2017 - pubs.rsc.org
Nitrogen-containing heterocyclic compounds and their derivatives have historically been
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …

Pharmacological significance of nitrogen-containing five and six-membered heterocyclic scaffolds as potent cholinesterase inhibitors for drug discovery

RJ Obaid, EU Mughal, N Naeem, MM Al-Rooqi… - Process …, 2022 - Elsevier
N-heterocycles are crucial due to their biological, chemical, and practical significance. They
are heavily investigated in biological processes involving anticancer, anti-inflammatory …

Recent developments in synthetic chemistry and biological activities of pyrazole derivatives

M Faisal, A Saeed, S Hussain, P Dar… - Journal of Chemical …, 2019 - Springer
Pyrazole, a five-membered heterocycle containing two nitrogen atoms, is extensively found
as a core framework in a huge library of heterocyclic compounds that envelops promising …

Recent Advances in the Green Synthesis of Active N-Heterocycles and Their Biological Activities

S Majee, Shilpa, M Sarav, BK Banik, D Ray - Pharmaceuticals, 2023 - mdpi.com
N-heterocyclic scaffolds represent a privileged architecture in the process of drug design
and development. It has widespread occurrence in synthetic and natural products, either …

New s-Triazine/Tetrazole conjugates as potent antifungal and antibacterial agents: Design, molecular docking and mechanistic study

RA Mekheimer, GEDA Abuo-Rahma… - Journal of Molecular …, 2022 - Elsevier
A novel hybrid N 2-(tetrazol-5-yl)-6-substituted-5, 6-dihydro-1, 3, 5-triazine-2, 4-diamines
have been synthesized in excellent yields through one-pot multi-component reaction of 5 …

A review on the synthesis and pharmacological activity of heterocyclic compounds

J Baranwal, S Kushwaha, S Singh… - Current Physical …, 2023 - ingentaconnect.com
Biologically active compounds play a very important role in our daily life. Almost all
biologically active compounds contain heteroatoms and among these, a major portion is …

Recent investigations into synthesis and pharmacological activities of phenoxy acetamide and its derivatives (chalcone, indole and quinoline) as possible therapeutic …

FH Al-Ostoot, Zabiulla, S Salah, SA Khanum - Journal of the Iranian …, 2021 - Springer
Medicinal chemistry can rightfully be regarded as a cornerstone in the public health of our
modern society that combines chemistry and pharmacology with the aim of designing and …

Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

A Palmieri, M Petrini - Natural product reports, 2019 - pubs.rsc.org
Covering: up to 2018 Tryptophol (indole-3-ethanol) is a metabolite produced by plants,
bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and …