Trachoma

HR Taylor, MJ Burton, D Haddad, S West, H Wright - The Lancet, 2014 - thelancet.com
Trachoma is the most common infectious cause of blindness. Repeated episodes of
infection with Chlamydia trachomatis in childhood lead to severe conjunctival inflammation …

Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis

WL Beatty, RP Morrison, GI Byrne - Microbiological reviews, 1994 - Am Soc Microbiol
Chlamydiae are medically important bacteria responsible for a wide range of human
infections and diseases. Repeated episodes of infection promote chronic inflammation …

Diagnosis and assessment of trachoma

AW Solomon, RW Peeling, A Foster… - Clinical microbiology …, 2004 - Am Soc Microbiol
Trachoma is caused by Chlamydia trachomatis. Clinical grading with the WHO simplified
system can be highly repeatable provided graders are adequately trained and standardized …

A critical review of the SAFE strategy for the prevention of blinding trachoma

H Kuper, AW Solomon, J Buchan… - The Lancet infectious …, 2003 - thelancet.com
Trachoma is an ocular disease caused by repeated infection with Chlamydia trachomatis. It
is the leading cause of infectious blindness globally, responsible for 5· 9 million cases of …

Global elimination of trachoma: how frequently should we administer mass chemotherapy?

T Lietman, T Porco, C Dawson, S Blower - Nature medicine, 1999 - nature.com
Abstract The World Health Organization has recommended repeat mass drug administration
as part of their global initiative to eliminate blinding trachoma by the year 2020. The efficacy …

Diagnosis of Chlamydia trachomatis eye infection in Tanzania by polymerase chain reaction/enzyme immunoassay

L Bobo, R Viscidi, T Quinn, S West, H Mkocha… - The Lancet, 1991 - Elsevier
Detection of Chlamydia trachomatis eye infection is largely unsatisfactory by standard
laboratory methods. A polymerase chain reaction/enzyme immunoassay (PCR-EIA) that had …

Clinical examination and laboratory tests for estimation of trachoma prevalence in a remote setting: what are they really telling us?

HR Wright, HR Taylor - The Lancet infectious diseases, 2005 - thelancet.com
Worldwide, an estimated 84 million people have active trachoma and 7· 6 million people
have trachomatous trichiasis. WHO's SAFE strategy is an effective tool in the worldwide effort …

[PDF][PDF] Comparison of two azithromycin distribution strategies for controlling trachoma in Nepal

SO Holm, HC Jha, RC Bhatta… - Bulletin of the World …, 2001 - SciELO Public Health
OBJECTIVE: The study compares the effectiveness of two strategies for distributing
azithromycin in an area with mild-to-moderate active trachoma in Nepal. METHODS: The …

[PDF][PDF] Blinding trachoma: prevention with the safe strategy

SK West - American Journal of Tropical Medicine and Hygiene, 2003 - Citeseer
Trachoma, the second leading cause of blindness worldwide, differentially affects the
poorest communities, which may have the least access to resources. With the establishment …

[PDF][PDF] Trachoma: the forgotten cause of blindness

B Muñoz, S West - Epidemiologic reviews, 1997 - Citeseer
Trachoma, the second leading cause of blindness world wide, continues to be
hyperendemic in many areas of Africa, Asia, and the Middle East. Caused by an ocular …