Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …

▪ Abstract Toxic shock syndrome (TSS) is an acute onset illness characterized by fever, rash
formation, and hypotension that can lead to multiple organ failure and lethal shock, as well …

The bacterial superantigens are protein toxins that bind to major histocompatibility complex
class II and T‐cell receptor to stimulate large numbers of T cells. The majority are produced …

The group A streptococcus (GAS)(Streptococcus pyogenes) is among the most common and
versatile of human pathogens. It is responsible for a wide spectrum of human diseases …

Superantigens (SAgs) are the most powerful T cell mitogens ever discovered.
Concentrations of less than 0· 1 pg/ml of a bacterial superantigen are sufficient to stimulate …

This Handbook on Metalloproteins focuses on the available structural information of proteins
and their metal ion coordination spheres. It centers on the metal ions indispensable for life …

▪ Abstract Superantigens (SAGs) are a class of immunostimulatory and disease-causing
proteins of bacterial or viral origin with the ability to activate large fractions (5–20%) of the T …

Zinc is important. It is the second most abundant trace metal with 2-4 grams in humans. It is
an essential trace element, critical for cell growth, development and differentiation, DNA …

The OB-fold is found in all three kingdoms and is well represented in both sequence and
structural databases. The OB-fold is a five-stranded closed β barrel and the majority of OB …

Staphylococcus aureus is an important human pathogen which is implicated in a wide
variety of diseases. Major determinants of the virulence of this organism include extracellular …