RNA‐dependent RNA polymerase of SARS‐CoV‐2 as a therapeutic target
Y Wang, V Anirudhan, R Du, Q Cui… - Journal of medical …, 2021 - Wiley Online Library
The global pandemic caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐
CoV‐2), named coronavirus disease 2019, has infected more than 8.9 million people …
CoV‐2), named coronavirus disease 2019, has infected more than 8.9 million people …
[HTML][HTML] Sofosbuvir: a novel oral agent for chronic hepatitis C
E Cholongitas, GV Papatheodoridis - Annals of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Major changes have emerged during the last few years in the therapy of patients with
chronic hepatitis C (CHC). Several direct acting antiviral agents (DAAs) have been …
chronic hepatitis C (CHC). Several direct acting antiviral agents (DAAs) have been …
Sofosbuvir as repurposed antiviral drug against COVID-19: why were we convinced to evaluate the drug in a registered/approved clinical trial?
B Sayad, M Sobhani, R Khodarahmi - Archives of medical research, 2020 - Elsevier
COVID-19 is a devastating global pandemic around the world. While the majority of infected
cases appear mild, in some cases individuals present respiratory complications with …
cases appear mild, in some cases individuals present respiratory complications with …
Cu from dissolution of CuO nanoparticles signals changes in root morphology
J Adams, M Wright, H Wagner, J Valiente, D Britt… - Plant physiology and …, 2017 - Elsevier
Abstract Utilization of CuO nanoparticles (NPs) in agriculture, as fertilizers or pesticides,
requires understanding of their impact on plant metabolism. Inhibition of root elongation by …
requires understanding of their impact on plant metabolism. Inhibition of root elongation by …
HCV genotype 3–the new treatment challenge
J Ampuero, M Romero‐Gomez… - Alimentary …, 2014 - Wiley Online Library
Background Over the past several years, hepatitis C therapy has been pegylated interferon
and ribavirin based. Although protease inhibitor‐based therapy has enhanced response …
and ribavirin based. Although protease inhibitor‐based therapy has enhanced response …
How to use COVID-19 antiviral drugs in patients with chronic kidney disease
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …
[HTML][HTML] Sofosbuvir, a significant paradigm change in HCV treatment
T McQuaid, C Savini, S Seyedkazemi - Journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Nucleotide compounds like sofosbuvir, acyclovir, and tenofovir have proven to be amongst
the most potent orally available antiviral treatments. These drugs exhibit high efficacy and a …
the most potent orally available antiviral treatments. These drugs exhibit high efficacy and a …
Emergence of resistance-associated variants during sofosbuvir treatment in chronically infected hepatitis E patients
A Gömer, M Klöhn, M Jagst, MK Nocke, S Pischke… - Hepatology, 2023 - journals.lww.com
Conclusions: In conclusion, viral population dynamics played a critical role during antiviral
treatment. High population diversity during sofosbuvir treatment led to the selection of …
treatment. High population diversity during sofosbuvir treatment led to the selection of …
Chronic hepatitis C: advances in therapy and the remaining challenges
SA Alqahtani, MS Sulkowski - Medical Clinics, 2023 - medical.theclinics.com
It is estimated that 58 million people suffer from chronic hepatitis C virus (HCV) infection
worldwide, which significantly contributes to chronic liver disease and liverrelated mortality …
worldwide, which significantly contributes to chronic liver disease and liverrelated mortality …
The discovery of sofosbuvir: a revolution for therapy of chronic hepatitis C
I Gentile, AE Maraolo, AR Buonomo… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Hepatitis C virus (HCV) infection is a worldwide health problem, whose
management has been revolutionized after the availability of sofosbuvir, a direct-acting …
management has been revolutionized after the availability of sofosbuvir, a direct-acting …