Tissue damage and inflammation are important triggers for regeneration and fibrosis. Tissue
damage not only induces inflammation in general, it also determines the type and …

BACKGROUND Uterine leiomyoma (also known as fibroid or myoma) is the most common
benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can …

The IL-1 cytokine family comprises 11 members (7 ligands with agonist activity, 3 receptor
antagonists and 1 anti-inflammatory cytokine) and is recognised as a key mediator of …

A diverse group of toxicants has been identified that cause injury to the lung including gases
(eg, ozone, chlorine), particulates/aerosols (eg, diesel exhaust, fly ash, other combustion …

Pulmonary fibrosis (PF) is a growing clinical problem which can result in breathlessness or
respiratory failure and has an average life expectancy of 3 years from diagnosis …

The concept of the inflammasome, a macromolecular complex sensing cell stress or danger
signals and initiating inflammation, was first introduced approximately a decade ago …

Silicosis caused by inhalation of silica particles leads to more than ten thousand new
occupational exposure-related deaths yearly. Exacerbating this issue, there are currently …

Pulmonary fibrosis is a chronic debilitating condition characterized by progressive
deposition of connective tissue, leading to a steady restriction of lung elasticity, a decline in …

Inhalation of crystalline silica particles leads to pulmonary fibrosis, eventually resulting in
respiratory failure and death. There are few effective drugs that can delay the progression of …

Twin birth rates have increased markedly in developed countries since the 1970s for two
primary reasons: increasing maternal age and the advent and increasing use of fertility …