Silicosis is a lung inflammatory disease caused by chronic exposure to crystalline silica
(CS). Leukotriene B 4 (LTB 4) plays an important role in neutrophilic inflammation, which …

Recurrent low back pain after spinal surgeries, such as lumbar laminectomy, is a major
complication of excessive epidural fibrosis. Although multiple preclinical and clinical …

Blue honeysuckles are rich in polyphenol compounds that exert many beneficial effects.
Previously, we demonstrated that polyphenol-rich blue honeysuckle extract (BHE) could …

The activation of NLRP3 results in the assembly of inflammasome that regulates caspase-1
activation and the subsequent secretion of bioactive interleukin (IL)-1β. Excessive activation …

Background Inhalation of dust containing silica particles is associated with severe
pulmonary inflammation and lung injury leading to chronic silicosis including fibrotic …

Current epidemiological studies suggest that crystalline silica exposure is associated with
an increased risk of cardiovascular and renal disease; however, the potential pathological …

Background Silicosis is a lung disease of fibrotic nature resulting from the inhalation and
deposition of dust containing crystalline silica. Subjects exposed to the same environmental …

Uterine fibroids (myomas or leiomyomas) are common benign tumors of reproductive aged
women. Fibroids are clinically apparent in 20–50% of women, and cause abnormal uterine …

Purpose: Impaired mucociliary clearance is an initial characteristic of recurrent cough,
respiratory infection and chronic respiratory diseases. It has been demonstrated that …

Environmental exposure to crystalline silica particles can lead to silicosis, which is one of the
most serious pulmonary interstitial fibrosis around the world. Unfortunately, the exact …