Chronic obstructive pulmonary disease patient care must include confirming a diagnosis
with postbronchodilator spirometry. Because of the clinical heterogeneity and the reality that …

Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …

Extract In the most recent 2023 report, the Global Initiative for Chronic Obstructive Lung
Disease (GOLD) committee recommends to no longer consider the degree of dyspnoea …

Effectiveness of single-inhaler triple therapy on exacerbation risk and mortality in COPD is
exaggerated in IMPACT and ETHOS trials from confounding by prior ICS discontinuation …

BACKGROUND: Clinical practice guidelines recommend dual long-acting muscarinic
antagonists (LAMAs)/long-acting β2agonists (LABAs) as maintenance therapy in patients …

Background Inhaled corticosteroid (ICS) therapy has been demonstrated to reduce the risk
of COPD exacerbations. It should only be prescribed to COPD patients who are not …

Purpose Real-life research is needed to evaluate the effectiveness of budesonide/
glycopyrrolate/formoterol (BGF) in routine COPD primary care management. We assessed …

The randomized controlled trial (RCT) forms the basis for drug approval by regulatory
agencies. Observational studies using existing data from healthcare databases now also …

Background High blood eosinophils seem to predict exacerbations and response to inhaled
corticosteroids (ICS) treatment in patients with chronic obstructive pulmonary disease …

Purpose Chronic obstructive pulmonary disease (COPD) is a disease characterized by
frequent acute exacerbations (AEs), especially in severe and very severe cases. We aimed …