[HTML][HTML] Cytokines Focus: Pathogenic T cell cytokines in multiple sclerosis
CA Wagner, PJ Roqué… - The Journal of …, 2020 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous
system that is believed to have an autoimmune etiology. As MS is the most common …
system that is believed to have an autoimmune etiology. As MS is the most common …
Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages
DJ Donnelly, EE Longbrake, TM Shawler… - Journal of …, 2011 - Soc Neuroscience
Macrophages exert divergent effects in the injured CNS, causing either neurotoxicity or
regeneration. The mechanisms regulating these divergent functions are not understood but …
regeneration. The mechanisms regulating these divergent functions are not understood but …
Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis
AM McGinley, SC Edwards, M Raverdeau… - Journal of …, 2018 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …
(MS) that shares many features with the human disease. This review will focus on the role of …
Development and homeostasis of “resident” myeloid cells: the case of the microglia
Microglia, macrophages of the central nervous system, play an important role in brain
homeostasis. Their origin has been unclear. Recent fate‐mapping experiments have …
homeostasis. Their origin has been unclear. Recent fate‐mapping experiments have …
Microglia diversity in health and multiple sclerosis
S Zia, KS Rawji, NJ Michaels, M Burr, BJ Kerr… - Frontiers in …, 2020 - frontiersin.org
Multiple Sclerosis (MS) is a neurodegenerative disease characterized by multiple focal
lesions, ongoing demyelination and, for most people, a lack of remyelination. MS lesions are …
lesions, ongoing demyelination and, for most people, a lack of remyelination. MS lesions are …
On the armament and appearances of human myeloid-derived suppressor cells
I Poschke, R Kiessling - Clinical immunology, 2012 - Elsevier
Myeloid-derived suppressor cells (MDSC) have frequently been observed in patients with
cancer. This heterogeneous population of myeloid cells can exert potent suppression of …
cancer. This heterogeneous population of myeloid cells can exert potent suppression of …
Mechanisms regulating regional localization of inflammation during CNS autoimmunity
E Pierson, SB Simmons, L Castelli… - Immunological …, 2012 - Wiley Online Library
Multiple sclerosis (MS) is a disease of the central nervous system (CNS) characterized by
inflammatory, demyelinating lesions localized in the brain and spinal cord. Experimental …
inflammatory, demyelinating lesions localized in the brain and spinal cord. Experimental …
Unravelling the genetic basis of schizophrenia and bipolar disorder with GWAS: A systematic review
Objectives To systematically review findings of GWAS in schizophrenia (SZ) and in bipolar
disorder (BD); and to interpret findings, with a focus on identifying independent replications …
disorder (BD); and to interpret findings, with a focus on identifying independent replications …
Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology
The nuclear factor kappa B (NF-κB) signaling cascade plays a critical role in the regulation
of immune and inflammatory responses and has been implicated in the pathogenesis of …
of immune and inflammatory responses and has been implicated in the pathogenesis of …
Recent advances in the mechanisms of neuroinflammation and their roles in neurodegeneration
R Niranjan - Neurochemistry international, 2018 - Elsevier
Neuroinflammation is associated with the pathogenesis of many neurological disorders
including Parkinson's disease, Alzheimer's disease, Amyotrophic lateral sclerosis and …
including Parkinson's disease, Alzheimer's disease, Amyotrophic lateral sclerosis and …