[HTML][HTML] Base excision repair in the immune system: small DNA lesions with big consequences
M Stratigopoulou, TP van Dam… - Frontiers in …, 2020 - frontiersin.org
The integrity of the genome is under constant threat of environmental and endogenous
agents that cause DNA damage. Endogenous damage is particularly pervasive, occurring at …
agents that cause DNA damage. Endogenous damage is particularly pervasive, occurring at …
Small-molecule inhibitors targeting FEN1 for cancer therapy
F Yang, Z Hu, Z Guo - Biomolecules, 2022 - mdpi.com
DNA damage repair plays a key role in maintaining genomic stability and integrity. Flap
endonuclease 1 (FEN1) is a core protein in the base excision repair (BER) pathway and …
endonuclease 1 (FEN1) is a core protein in the base excision repair (BER) pathway and …
Comprehensive network analysis reveals alternative splicing-related lncRNAs in hepatocellular carcinoma
It is increasingly appreciated that long non-coding RNAs (lncRNAs) associated with
alternative splicing (AS) could be involved in aggressive hepatocellular carcinoma. Although …
alternative splicing (AS) could be involved in aggressive hepatocellular carcinoma. Although …
Clinical and immunogenetic aspects of systemic lupus erythematosus
LVKS Bhaskar, GP Nagaraju - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Systemic lupus erythematosus (SLE) is an autoimmune disease triggered by a complex
interaction of immunologic, environmental, and genetic factors. Like other diseases of …
interaction of immunologic, environmental, and genetic factors. Like other diseases of …
Role of Some Apoptotic Proteins in Pathogenesis of Juvenile Systemic Lupus Erytheromatosis and Lupus Nephritis
AAA Hanna, HH Abdelnabi… - Journal of Advances …, 2022 - stm.e4journal.com
Background: Apoptosis is increased in Systemic Lupus Erytheromatosis (SLE) patients with
defective clearance of apoptotic cells, which lead to a pathological accumulation of …
defective clearance of apoptotic cells, which lead to a pathological accumulation of …