Nitro-fatty acid products of oxidative inflammatory reactions mediate anti-inflammatory cell
signalling responses. LNO2 (nitrolinoleic acid) induces expression of HO-1 (haem …

Nitrated fatty acids (NO2-FAs) are a newly discovered class of biologically active
compounds with distinct biochemical features that induce physiologically beneficial …

Complex lipids, phospholipids (PLs) and triacylglycerides (TAGs), are prone to modifications
induced by reactive nitrated species and reactive oxygen species, generating a range of …

Nitric oxide (• NO) is an essential molecule able to control and regulate many biological
functions. Additionally,• NO bears a potential toxicity or damaging effects under conditions of …

Although peroxynitrite (ONOO−) has been well documented as a nitrating cognate of nitric
oxide (NO) in plant cells, modifications of proteins, fatty acids, and nucleotides by nitration …

Modern society has changed its diet composition, transitioning to a higher intake of
saturated fat with a 50% increase of cardiovascular risk (CVD). Within the context of …

Nitration of arachidonic acid (AA) to nitroarachidonic acid (AANO2) leads to anti-
inflammatory intracellular activities during macrophage activation. However, less is known …

Nitrogen dioxide (NO2) is an important oxidant molecule in biology that is produced by
several biological processes, and it is also an important air pollutant. It can oxidize proteins …

Background Inflammatory-mediated pathological processes in the endothelium arise as a
consequence of the dysregulation of vascular homeostasis. Of particular importance are …

Abstract Nitro-fatty acids (NO 2-FA) are electrophilic signaling mediators formed in tissues
during inflammation, which are able to induce pleiotropic cytoprotective and antioxidant …