Peripheral nerves injuries result in paralysis, anesthesia and lack of autonomic control of the
affected body areas. After injury, axons distal to the lesion are disconnected from the …

▪ Abstract Nerve regeneration is a complex biological phenomenon. In the peripheral
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …

In spite of an enormous amount of new experimental laboratory data based on evolving
neuroscientific concepts during the last 25 years peripheral nerve injuries still belong to the …

Wallerian degeneration of the distal stump of a severed peripheral nerve involves invasion
by myelomonocytic cells, whose presence is necessary for destruction of myelin and for …

The goal of this work was to utilize the naturally derived bioactive polymer hyaluronic acid
(HA) to create a combination tissue engineering scaffold and protein delivery device. HA is a …

Biological nerve grafts have been extensively utilized in the past to repair peripheral nerve
injuries. More recently, the use of synthetic guidance tubes in repairing these injuries has …

Terminal Schwann cells overlying the neuromuscular junction sprout elaborate processes
upon muscle denervation. We show here that motor axons use these processes as …

Alternatives to autografts have long been sought for use in bridging neural gaps. Many
entubulation materials have been studied, although with generally disappointing results in …

Nerve segments approximately 7 mm long were excised from the predegenerated sciatic
nerves of mice, and treated 5 times by repetitive freezing and thawing to kill the Schwann …

Wallerian degeneration is a cascade of stereotypical events in reaction to injury of nerve
fibres. These events consist of cellular and molecular alterations, including macrophage …