The extracellular matrix (ECM) is a complex network with multiple functions, including
specific functions during tissue regeneration. Precisely, the properties of the ECM have been …

Bone is a dynamic organ with high regenerative potential and provides essential biological
functions in the body, such as providing body mobility and protection of internal organs …

Critical-sized bone defects caused by traumatic fractures, tumour resection and congenital
malformation are unlikely to heal spontaneously. Bone tissue engineering is a promising …

While some clinical advances in cartilage repair have occurred, osteochondral (OC) defect
repair remains a significant challenge, with current scaffold-based approaches failing to …

The development of bone-like tissues in vitro that exhibit key features similar to those in vivo
is needed to produce tissue models for drug screening and the study of bone physiology …

Tissue engineering provides a new approach for the treatment of osteochondral defects.
However, the lack of an ideal double-layer scaffold with osteochondral-biomimetic …

In order to repair critical‐sized bone defects, various polylactic acid‐glycolic acid (PLGA)‐
based hybrid scaffolds are successfully developed as bone substitutes. However, the …

In bone tissue engineering, the design of in vitro models able to recreate both the chemical
composition, the structural architecture, and the overall mechanical environment of the …

The decellularized extracellular matrix (dECM) is capable of promoting stem cell
proliferation, migration, adhesion, and differentiation. It is a promising biomaterial for …

Fibrocartilage enthesis is the junction between bone and tendon with a typical
characteristics of fibrocartilage transition zones. The regeneration of this transition zone is …