[HTML][HTML] Systematic review and meta-analysis: efficacy of pharmacological interventions for irritability and emotional dysregulation in autism spectrum disorder and …

GS de Pablo, CP Jorda, J Vaquerizo-Serrano… - Journal of the American …, 2023 - Elsevier
Objective Emotional dysregulation and irritability are common in individuals with autism
spectrum disorder (ASD). We conducted the first meta-analysis assessing the efficacy of a …

What is autism?

P Joon, A Kumar, M Parle - Pharmacological reports, 2021 - Springer
The term “Autism spectrum disorder”(ASD), in vogue at present, has evolved after continual
substantial developments taking place over more than a century. ASD is a heterogeneous …

[HTML][HTML] Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder

LM Schmitt, EG Smith, EV Pedapati, PS Horn, M Will… - Scientific Reports, 2023 - nature.com
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized
by core impairments in social communication as well as restricted, repetitive patterns of …

Decades of progress in the psychopharmacology of autism spectrum disorder

E Henneberry, M Lamy, KC Dominick… - Journal of Autism and …, 2021 - Springer
Recent decades have been marked by a wave drug treatment research in autism spectrum
disorder (ASD). This work has resulted in improved ability to treat commonly occurring …

Drug treatment of epilepsy neuropsychiatric comorbidities in children

GL Holmes - Pediatric Drugs, 2021 - Springer
There is increasing recognition that epilepsy can be associated with a broad spectrum of
comorbidities. While epileptic seizures are an essential element of epilepsy in children …

[HTML][HTML] Neuroprotective effects of quercetin in pediatric neurological diseases

L Alvarez-Arellano, M Salazar-García, JC Corona - Molecules, 2020 - mdpi.com
Oxidative stress is a crucial event underlying several pediatric neurological diseases, such
as the central nervous system (CNS) tumors, autism spectrum disorder (ASD) and attention …

Emerging drugs for the treatment of irritability associated with autism spectrum disorder

A Shamabadi, H Karimi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is an early-onset disorder with a prevalence of
1% among children and reported disability-adjusted life years of 4.31 million. Irritability is a …

[HTML][HTML] Risperidone or aripiprazole can resolve autism core signs and symptoms in young children: Case study

HA Alsayouf, H Talo, ML Biddappa, E De Los Reyes - Children, 2021 - mdpi.com
Risperidone and aripiprazole are approved by the USA Food and Drug Administration for
the treatment of irritability and aggression in children from the ages of 5 and 6 years …

[HTML][HTML] Alterations of regional homogeneity in preschool boys with autism spectrum disorders

Z Lan, S Xu, Y Wu, L Xia, K Hua, M Li, M Liu… - Frontiers in …, 2021 - frontiersin.org
Objectives The study was aimed at investigating the alterations of local spontaneous brain
activity in preschool boys with autism spectrum disorders (ASD). Methods Based on regional …

[HTML][HTML] Striatal increase of dopamine receptor 2 density in idiopathic and syndromic mouse models of autism spectrum disorder

S Chhabra, L Nardi, P Leukel, CJ Sommer… - Frontiers in …, 2023 - frontiersin.org
Autism spectrum disorder (ASD) comprises a wide range of neurodevelopmental
phenotypes united by impaired social interaction and repetitive behavior. Environmental and …