Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease
Therapies targeting late events in Alzheimer's disease (AD), including aggregation of
amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they …
amyloid beta (Aβ) and hyperphosphorylated tau, have largely failed, probably because they …
Concurrent fNIRS and EEG for brain function investigation: a systematic, methodology-focused review
Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) stand as
state-of-the-art techniques for non-invasive functional neuroimaging. On a unimodal basis …
state-of-the-art techniques for non-invasive functional neuroimaging. On a unimodal basis …
Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association
Mounting evidence has firmly established that low levels of cardiorespiratory fitness (CRF)
are associated with a high risk of cardiovascular disease, all-cause mortality, and mortality …
are associated with a high risk of cardiovascular disease, all-cause mortality, and mortality …
Neurovascular coupling: motive unknown
PJ Drew - Trends in neurosciences, 2022 - cell.com
In the brain, increases in neural activity drive changes in local blood flow via neurovascular
coupling. The common explanation for increased blood flow (known as functional …
coupling. The common explanation for increased blood flow (known as functional …
Mapping the fine-scale organization and plasticity of the brain vasculature
The cerebral vasculature is a dense network of arteries, capillaries, and veins. Quantifying
variations of the vascular organization across individuals, brain regions, or disease models …
variations of the vascular organization across individuals, brain regions, or disease models …
Alzheimer's disease: a matter of blood–brain barrier dysfunction?
The blood–brain barrier (BBB) keeps neurotoxic plasma-derived components, cells, and
pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown in …
pathogens out of the brain. An early BBB breakdown and/or dysfunction have been shown in …
The role of NADPH oxidases and oxidative stress in neurodegenerative disorders
A Tarafdar, G Pula - International journal of molecular sciences, 2018 - mdpi.com
For a number of years, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases
(NOX) was synonymous with NOX2/gp91phox and was considered to be a peculiarity of …
(NOX) was synonymous with NOX2/gp91phox and was considered to be a peculiarity of …
Defining the relationship between hypertension, cognitive decline, and dementia: a review
KA Walker, MC Power, RF Gottesman - Current hypertension reports, 2017 - Springer
Hypertension is a highly prevalent condition which has been established as a risk factor for
cardiovascular and cerebrovascular disease. Although the understanding of the relationship …
cardiovascular and cerebrovascular disease. Although the understanding of the relationship …
[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …
incidence and prevalence of dementia increases, and the need to understand the etiology …