Mammalian skeletal muscle comprises different fiber types, whose identity is first established
during embryonic development by intrinsic myogenic control mechanisms and is later …

Physical activity plays an important role in preventing chronic disease in adults and the
elderly. Exercise has beneficial effects on the nervous system, including at the …

Nuclear receptor signaling plays an important role in energy metabolism. In this study we
demonstrate that the nuclear receptor corepressor RIP140 is a key regulator of metabolism …

Background Skeletal muscle is a complex, versatile tissue composed of a variety of
functionally diverse fiber types. Although the biochemical, structural and functional …

Skeletal muscle is composed of different myofiber types that preferentially use glucose or
lipids for ATP production. How fuel preference is regulated in these post-mitotic cells is …

Purpose To evaluate the safety and feasibility of combining exercise (EX) and resveratrol to
treat older adults with physical function limitations. Methods Three-arm, two-site pilot …

Satellite cells are companions to voluntary muscle fibres, and are named for their intimate
positional orsatellite'relationship, as if revolving around fibres, like a satellite moon around …

Obesity and its associated complications, which can lead to the development of metabolic
syndrome, are a worldwide major public health concern especially in developed countries …

Denervation deeply affects muscle structure and function, the alterations being different in
slow and fast muscles. Because the effects of denervation on fast muscles are still …

Limb girdle muscular dystrophy 2A is due to loss-of-function mutations in the Calpain 3
(CAPN3) gene. Our previous data suggest that CAPN3 helps to maintain the integrity of the …