Incremental prognostic value of acute serum biomarkers for functional outcome after traumatic brain injury (CENTER-TBI): an observational cohort study
Background Several studies have reported an association between serum biomarker values
and functional outcome following traumatic brain injury. We aimed to examine the …
and functional outcome following traumatic brain injury. We aimed to examine the …
Concussion guidelines step 2: evidence for subtype classification
BACKGROUND Concussion is a heterogeneous mild traumatic brain injury (mTBI)
characterized by a variety of symptoms, clinical presentations, and recovery trajectories. By …
characterized by a variety of symptoms, clinical presentations, and recovery trajectories. By …
A serum protein biomarker panel improves outcome prediction in human traumatic brain injury
E Thelin, F Al Nimer, A Frostell, H Zetterberg… - Journal of …, 2019 - liebertpub.com
Brain-enriched protein biomarkers of tissue fate are being introduced clinically to aid in
traumatic brain injury (TBI) management. The aim of this study was to determine how …
traumatic brain injury (TBI) management. The aim of this study was to determine how …
[HTML][HTML] Multiclass semantic segmentation and quantification of traumatic brain injury lesions on head CT using deep learning: an algorithm development and …
Background CT is the most common imaging modality in traumatic brain injury (TBI).
However, its conventional use requires expert clinical interpretation and does not provide …
However, its conventional use requires expert clinical interpretation and does not provide …
Functional recovery, symptoms, and quality of life 1 to 5 years after traumatic brain injury
Importance Many level I trauma center patients experience clinical sequelae at 1 year
following traumatic brain injury (TBI). Longer-term outcome data are needed to develop …
following traumatic brain injury (TBI). Longer-term outcome data are needed to develop …
Impact of duration and magnitude of raised intracranial pressure on outcome after severe traumatic brain injury: a CENTER-TBI high-resolution group study
Magnitude of intracranial pressure (ICP) elevations and their duration have been associated
with worse outcomes in patients with traumatic brain injuries (TBI), however published …
with worse outcomes in patients with traumatic brain injuries (TBI), however published …
Brain–immune interactions and neuroinflammation after traumatic brain injury
Traumatic brain injury (TBI) is the principal cause of death and disability in children and
young adults. Clinical and preclinical research efforts have been carried out to understand …
young adults. Clinical and preclinical research efforts have been carried out to understand …
Prognosis in moderate and severe traumatic brain injury: a systematic review of contemporary models and validation studies
SA Dijkland, KA Foks, S Polinder, DWJ Dippel… - Journal of …, 2020 - liebertpub.com
Outcome prognostication in traumatic brain injury (TBI) is important but challenging due to
heterogeneity of the disease. The aim of this systematic review is to present the current state …
heterogeneity of the disease. The aim of this systematic review is to present the current state …
Individualizing thresholds of cerebral perfusion pressure using estimated limits of autoregulation
J Donnelly, M Czosnyka, H Adams, C Robba… - Critical care …, 2017 - journals.lww.com
Objectives: In severe traumatic brain injury, cerebral perfusion pressure management based
on cerebrovascular pressure reactivity index has the potential to provide a personalized …
on cerebrovascular pressure reactivity index has the potential to provide a personalized …
Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness …
EJA Wiegers, HF Lingsma, JA Huijben… - The Lancet …, 2021 - thelancet.com
Background Fluid therapy—the administration of fluids to maintain adequate organ tissue
perfusion and oxygenation—is essential in patients admitted to the intensive care unit (ICU) …
perfusion and oxygenation—is essential in patients admitted to the intensive care unit (ICU) …