Moderate-to-severe traumatic brain injury (TBI) remains a major global challenge, with rising
incidence, unchanging mortality and lifelong impairments. State-of-the-science reviews are …

Background Traumatic brain injury (TBI) is an important global public health burden, where
those injured by high-energy transfer (eg, road traffic collisions) are assumed to have more …

Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …

In the context of traumatic brain injury (TBI), decompressive craniectomy (DC) is used as part
of tiered therapeutic protocols for patients with intracranial hypertension (secondary or …

Background Traumatic brain injury (TBI) is a major contributor to morbidity and mortality.
Computerized tomography (CT) scanning of the brain is essential for diagnostic screening of …

Purpose Indications and optimal timing for tracheostomy in traumatic brain-injured (TBI)
patients are uncertain. This study aims to describe the patients' characteristics, timing, and …

Chronic post-concussive symptoms are common after mild traumatic brain injury (mTBI) and
are difficult to predict or treat. Thalamic functional integrity is particularly vulnerable in mTBI …

Background We aimed to understand the relationship between serum biomarker
concentration and lesion type and volume found on computed tomography (CT) following all …

Background No definitive evidence exists on how intracranial hypertension should be
treated in patients with traumatic brain injury (TBI). It is therefore likely that centers and …

Importance Advances in treatment of traumatic brain injury are hindered by the inability to
monitor pathological mechanisms in individual patients for targeted neuroprotective …