Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …

The ability to genetically manipulate a pathogen is fundamental to discovering factors
governing host-pathogen interactions at the molecular level and is critical for devising …

Invasive microbial pathogens often disrupt epithelial barriers, yet the mechanisms used to
dismantle tight junctions are poorly understood. Here, we show that the obligate pathogen …

The obligate intracellular bacterium Chlamydia trachomatis is the causative agent of the
most frequently reported bacterial sexually transmitted disease. Upon internalization into …

Although progress in Chlamydia genetics has been rapid, genomic modification has
previously been limited to point mutations and group II intron insertions which truncate …

Chlamydia species infect millions of individuals worldwide and are important etiological
agents of sexually transmitted disease, infertility, and blinding trachoma. Historically, the …

Chlamydia trachomatis is an obligate intracellular pathogen that is the etiological agent of a
variety of human diseases, including blinding trachoma and sexually transmitted infections …

Chlamydia trachomatis infections are the leading cause of sexually transmitted infections of
bacterial origin. Lower genital tract infections are often asymptomatic, and therefore left …

Chlamydia trachomatis is the leading cause of infectious blindness and a sexually
transmitted infection. All chlamydiae are obligate intracellular bacteria that replicate within a …

As obligate intracellular bacteria, Chlamydia spp. have evolved numerous, likely intricate,
mechanisms to create and maintain a privileged intracellular niche. Recent progress in …