The present rapid growth in the availability of safe and effective vaccines provides a
continuing need to expand and simplify vaccine administration programs. The replacement …

This review offers a perspective on the acellular pertussis vaccine efficiency trials concluded
in the 1990s and presents the main conclusions of a meta-analysis of 52 studies that …

When pertussis toxin S1 subunit and pertactin structural genes in Bordetella pertussis
clinical isolates from France and Germany were sequenced, 3 previously described S1 …

The availability of combined vaccines containing protective antigens against the majority of
(ideally all) diseases for which universal immunization is recommended in infancy would …

The number of recommended vaccines that require injections has increased substantially
over the last 13 years. The schedule for active immunization of healthy infants and children …

Background. The changing epidemiology of pertussis in France has emphasized the need
for booster vaccinations in adolescents. Although not previously recommended because of …

Abstract Background In Turkey, several changes have been made in the vaccination
schedule. Vaccines against diphtheria, tetanus, pertussis and poliomiyelitis were applied as …

This study investigated the immunogenicity and safety of including a Haemophilus
influenzae type b vaccine (polyribosylribitol phosphate conjugated to tetanus toxoid, PRP-T) …

Vaccines against bioterrorism agents offer the prospect of providing high levels of protection
against airborne pathogens. However, the diversity of the bioterrorism threat means that it …

After 2 decades of development, acellular pertussis vaccines are becoming more widely
available for use. Products that contain from 1 to 5 purified antigens of Bordetella pertussis …