Bisphosphonates are considered the most effective drugs for controlling adult and pediatric
osteolytic diseases. Although they have been used successfully for many years, several side …

Osteogenesis imperfecta type III (OI) is a serious genetic condition with poor bone quality
and a high fracture rate in children. In a previous study, it was shown that a monoclonal …

Abstract Background Osteogenesis Imperfecta (OI) is a rare genetic condition characterised
by increased bone fragility. Recurrent fractures, pain and fatigue have a considerable impact …

Bone microarchitecture has been shown to provide useful information regarding the
evaluation of skeleton quality with an added value to areal bone mineral density, which can …

Osteogenesis imperfecta (OI) is a rare hereditary skeletal dysplasia, characterized by
recurrent fractures and bone deformity. This study presents a clinical characterization and …

Background Squamous cell carcinomas of the lung are an extremely common and deadly
form of non-small cell lung cancers. Clinical management of the disease is dependent on …

Abstract Pediatric patients with Osteogenesis Imperfecta (OI), a heritable connective tissue
disorder, frequently suffer from long bone deformations. Surgical correction often results in …

Osteogenesis imperfecta (OI) is a large group of genetically heterogeneous diseases
resulting from decreased bone density and an abnormal microarchitecture, which are …

Osteogenesis imperfecta type XI (OI-XI) and Bruck syndrome type I (BS1) are two rare
disorders caused by biallelic variants in the FKBP10, characterized by early-onset bone …

Abstract Background Osteogenesis Imperfecta (OI) is a rare genetic condition whose key
characteristic is increased bone fragility. OI has the potential to impact upon all family …