Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

BACKGROUND Modern lifestyle has led to an increase in the age at conception. Advanced
age is one of the critical risk factors for female-related infertility. It is well known that maternal …

Progressive loss of physiological integrity and accumulation of degenerative changes
leading to functional impairment and increased susceptibility to diseases are the main …

The ovary ages earlier than most other tissues, yet the underlying mechanisms remain
elusive. Here a comprehensive analysis of transcriptomic landscapes in different organs in …

Biological sex is a factor in many conditions, including aging, neurodegenerative disease,
cancer, and more. For each of these, men and women display distinct differences in disease …

In brief Post-ovulatory ageing of oocytes leads to poor oocyte and embryo quality as well as
abnormalities in offspring. This review provides an update on the contributions of oxidative …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

The ovary has a comparatively short functional lifespan compared with other organs, and
genetic and pathological injuries can further shorten its functional life. Thus, preserving …

Estrogens are a group of steroid hormones that promote the development and maintenance
of the female reproductive system and secondary sex characteristics. Estrogens also …