[HTML][HTML] Clinical Implications of Basic Research: Exploring the Transformative Potential of Spatial'Omics in Uro-oncology

S Figiel, A Bates, DA Braun, R Eapen, M Eckstein… - European Urology, 2024 - Elsevier
New spatial molecular technologies are poised to transform our understanding and
treatment of urological cancers. By mapping the spatial molecular architecture of tumours …

Updated Review on Analysis of long Non-coding RNAs as Emerging Diagnostic and Therapeutic Targets in Prostate Cancers

Z Ke, X Hu, Y Liu, D Shen, MI Khan, J Xiao - Critical Reviews in Oncology …, 2024 - Elsevier
Despite advancements, prostate cancers (PCa) are a significant global health due to
delayed diagnosis and therapeutic resistance. This review delves into the complex …

Should systematic prostatic biopsies be discontinued?

L Klotz - Prostate Cancer and Prostatic Diseases, 2024 - nature.com
Introduction The use of systematic biopsies in addition to targeted biopsies is based on
multiple studies showing that 15–20% of “clinically significant” cancers are missed on …

Radiotranscriptomics identified new mRNAs and miRNA markers for distinguishing prostate cancer from benign prostatic hyperplasia

Q Yang, Q Li, N Li, D Wang, S Niu, P Tang… - Cancer …, 2023 - Wiley Online Library
The present study investigated ultrasound (US) phenotypes reflecting prostate cancer (PCa)‐
related genetic mutations. Herein, integration of radiotranscriptomic data, US and contrast …

Contrast Agent Dynamics Determine Radiomics Profiles in Oncologic Imaging

ML Watzenboeck, L Beer, D Kifjak, S Röhrich… - Cancers, 2024 - mdpi.com
Simple Summary Radiomics is the extraction of high-dimensional quantitative features from
medical images. These features have shown potential to provide diagnostic and prognostic …

The Genomics and Natural History of MRI-Visible vs MRI-Invisible Prostate Cancers: Clinical Implications

L Klotz - Journal of Urology, 2024 - journals.lww.com
PROSPECTIVE randomized trials have demonstrated that targeted biopsy is superior to
systematic biopsy with respect to the diagnosis of grade group (GG) 2 or higher prostate …

Radiogenomics of Prostate Cancer: Current State and Future Directions

T Koca, RA Aksoy, E Bilek, AF Korcum - 2024 - Springer
Radiomic analysis, which has developed rapidly in recent years, has become extremely
popular as a promising subject for the future. Radiomic data obtained from prostate-specific …