[HTML][HTML] Progress in the application of sustained-release drug microspheres in tissue engineering

L Ruan, M Su, X Qin, Q Ruan, W Lang, M Wu, Y Chen… - Materials Today Bio, 2022 - Elsevier
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with
targeted and other effects. There are many types of sustained-release drug microspheres …

[HTML][HTML] An overview of the production methods for core–shell microspheres for parenteral controlled drug delivery

RS van der Kooij, R Steendam, HW Frijlink… - European Journal of …, 2022 - Elsevier
Core-shell microspheres hold great promise as a drug delivery system because they offer
several benefits over monolithic microspheres in terms of release kinetics, for instance a …

[HTML][HTML] Fabrication of biodegradable hollow microsphere composites made of polybutylene adipate co-terephthalate/polyvinylpyrrolidone for drug delivery and …

C Xie, Q Xiong, Y Wei, X Li, J Hu, M He, S Wei, J Yu… - Materials Today Bio, 2023 - Elsevier
Sustained drug release has attracted increasing interest in targeted drug therapy. However,
existing methods of drug therapy suffer drug action time, large fluctuations in the effective …

Development of lysozyme loaded microneedles for dermal applications

A Panda, A Shettar, PK Sharma, MA Repka… - International Journal of …, 2021 - Elsevier
Microneedles are being widely explored for dermal delivery of macromolecules. They have
the capability and the potential for entrapping enzymes such as lysozyme within a polymeric …

[HTML][HTML] PLGA/xylitol nanoparticles enhance antibiofilm activity via penetration into biofilm extracellular polymeric substances

A Anjum, PY Chung, SF Ng - RSC advances, 2019 - pubs.rsc.org
Biofilms are gelatinous masses of microorganisms attached to wound surfaces. Previous
studies suggest that biofilms generate resistance towards antibiotic treatments. It was …

Three months extended-release microspheres prepared by multi-microchannel microfluidics in beagle dog models

JH Kim, CH Ryu, CH Chon, S Kim, S Lee… - International Journal of …, 2021 - Elsevier
To evaluate in vivo drug release profiles in beagle dogs, finasteride-loaded PLGA
microspheres were prepared using a novel method of IVL-PPF Microsphere® microfluidic …

New long-acting injectable microspheres prepared by IVL-DrugFluidic™ system: 1-month and 3-month in vivo drug delivery of leuprolide

M Kim, JH Kim, S Kim, R Maharjan, NA Kim… - International journal of …, 2022 - Elsevier
The microspheres for 1-month (PLGA-based) and 3-month (PLA-based) drug releases of
leuprolide were manufactured using an IVL-DrugFluidic™ system and their morphology …

[HTML][HTML] Tailor-made fluorinated ionic liquids for protein delivery

NSM Vieira, PJ Castro, DF Marques, JMM Araújo… - Nanomaterials, 2020 - mdpi.com
Nowadays, pharmaceutical companies are facing several challenges with the development
and approval of new biological products. The unique properties of several fluorinated ionic …

Nanoscale cationic micelles of amphiphilic copolymers based on star-shaped PLGA and PEI cross-linked PEG for protein delivery application

J Wang, S Li, T Chen, W Xian, H Zhang, L Wu… - Journal of Materials …, 2019 - Springer
To enhance the bioavailability of protein therapeutants and improve the stability of storage
and delivery, a series of branched amphiphilic block copolymers consisting of cholic acid …

Complementary Effects of Porosigen and Stabilizer on the Structure of Hollow Porous Poly(lactic-co-glycolic acid) Microparticles

X Su, I Gupta, US Jonnalagadda… - ACS Applied Polymer …, 2020 - ACS Publications
Poly (lactic-co-glycolic acid)(PLGA) plays a pivotal role in both conventional and emerging
drug delivery applications. In this paper, we utilize a facile synthesis strategy to fabricate …