Mast cells are not only necessary for allergic reactions, but recent findings indicate that they
are also involved in a variety of neuroinflammatory diseases, especially those worsened by …

Psychological stresses are associated with cardiovascular diseases to the extent that
cardiovascular diseases are among the most important group of psychosomatic diseases …

Associations between stress and health outcomes have now been carefully documented,
but the mechanisms by which stress specifically influences disease susceptibility and …

Stress is defined as a state of threatened homeostasis. The principal effectors of the stress
system include corticotropin-releasing hormone, arginine vasopressin, the glucocorticoids …

Mast cells are well known for their involvement in allergic and anaphylactic reactions, but
recent findings implicate them in a variety of inflammatory diseases affecting different …

Osteoarthritis (OA) is one of the most common and disabling chronic joint disorders affecting
horses, dogs and humans. Synovial inflammation or synovitis is a frequently observed …

Urocortins, three paralogs of the stress-related peptide corticotropin-releasing factor (CRF)
found in bony fish, amphibians, birds, and mammals, have unique phylogenies …

Stress activates the hypothalamic-pituitary-adrenal axis through CRH, leading to production
of glucocorticoids that down-regulate immune responses. However, acute stress also has …

Nitric oxide (NO) is involved in stress physiology and stress-related disease processes. Like
stress, NO seems to be capable of principally exerting either beneficial or deleterious effects …

Proinflammation is a widespread phenomenon. It has an association with the stress (patho)
physiology and is connected with various diseases. Recently, it has been discussed if …