Does human papillomavirus cause cervical cancer? The state of the epidemiological evidence

N Munoz, X Bosch, JM Kaldor - British journal of cancer, 1988 - nature.com
The human papillomavirus has emerged over the past decade as the leading candidate to
be the sexually transmitted aetiological factor in cervical cancer. Although it appears that …

Epidemiology of genital papillomaviruses and cervical cancer

WC Reeves, WE Rawls… - Reviews of infectious …, 1989 - academic.oup.com
Cervical cancer is an extremely common disease. Its natural history has been well
described, and individual risk factors have been defined. It is clear from the epidemiologic …

Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA

L Pirisi, S Yasumoto, M Feller, J Doniger… - Journal of …, 1987 - Am Soc Microbiol
Human keratinocytes and fibroblasts isolated from foreskin were transformed by transfection
with recombinant human papillomavirus type 16 (HPV16) DNA. The transformed cells …

Detection and typing of multiple genital human papillomaviruses by DNA amplification with consensus primers

H Yoshikawa, T Kawana, K Kitagawa… - Japanese Journal of …, 1991 - Wiley Online Library
Many types of human papillomavirus (HPV) are associated with genital lesions. In order to
develop simple and sensitive diagnostic procedures for HPV infection, we took advantage of …

Integration of human papillomavirus type 16 into cellular DNA of cervical carcinoma: preferential deletion of the E2 gene and invariable retention of the long control …

KB Choo, CC Pan, SH Han - Virology, 1987 - Elsevier
The integration patterns of human papillomavirus (HPV) type 16 in the cellular DNA of six
cervical carcinoma samples were analyzed by the Southern blot procedure. None of the …

Both episomal and integrated forms of human papillomavirus type 16 are involved in invasive cervical cancers

T Matsukura, S Koi, M Sugase - Virology, 1989 - Elsevier
The form of human papillomavirus type 16 (HPV 16) DNA in specimens of invasive cervical
cancer was investigated. High molecular, tandem repeats of viral sequences were detected …

Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions

BC Das, JK Sharma… - Journal of General …, 1992 - microbiologyresearch.org
Integration of human papillomavirus (HPV) DNA into the host cell genome is believed to be
essential for malignant progression. However unambiguous detection of the physical state of …

A high frequency of human papillomavirus DNA sequences in cervical carcinomas of Indian women as revealed by Southern blot hybridization and polymerase chain …

BC Das, JK Sharma, V Gopalkrishna… - Journal of medical …, 1992 - Wiley Online Library
Ninety‐six colposcopical ly directed biopsies from squamous epithelial carcinoma of the
uterine cervix and 22 age‐matched normal control biopsy specimens were examined by …

Multiple infections in cases of cervical cancer from a high‐incidence area in tropical Africa

R Schmauz, P Okong, EM De Villiers… - … Journal of Cancer, 1989 - Wiley Online Library
The presence of several infections was determined in tissue and serum samples from 34
cases and 23 controls seen in 1984–85 at Mulago Hospital in Kampala, Uganda. When …

Human papillomavirus DNA in normal, metaplastic, preneoplastic and neoplastic epithelia of the cervix uteri

PG Fuchs, F Girardi, H Pfister - International journal of cancer, 1988 - Wiley Online Library
Colposcopically directed cervical punch biopsies from 362 patients were screened by
Southern blot hybridization for the presence of DNA of human papillomavirus (HPV) 6, 10 …