Deciphering the clinical significance of longitudinal antiphospholipid antibody titers
CB Chighizola, R Willis, G Maioli, S Sciascia… - Autoimmunity …, 2024 - Elsevier
In antiphospholipid syndrome (APS), the risk of clinical manifestations increases with higher
titers of antiphospholipid antibodies (aPL). Despite the adoption of aPL titers in the …
titers of antiphospholipid antibodies (aPL). Despite the adoption of aPL titers in the …
Rethinking antiphospholipid syndrome to guide future management and research
Antiphospholipid syndrome (APS) consists of thrombotic, non-thrombotic and obstetric
clinical manifestations developing in individuals with persistent antiphospholipid antibodies …
clinical manifestations developing in individuals with persistent antiphospholipid antibodies …
Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome
A Tambralli, A Harbaugh… - The Journal of …, 2024 - Am Soc Clin Investig
Neutrophil hyperactivity and neutrophil extracellular trap release (NETosis) appear to play
important roles in the pathogenesis of the thromboinflammatory autoimmune disease known …
important roles in the pathogenesis of the thromboinflammatory autoimmune disease known …
Systemic Lupus Erythematosus: A Review
CH Siegel, LR Sammaritano - JAMA, 2024 - jamanetwork.com
Importance Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by inflammation and immune-mediated injury to multiple organ systems …
characterized by inflammation and immune-mediated injury to multiple organ systems …
Diagnosis and management of catastrophic antiphospholipid Syndrome and the potential impact of the 2023 ACR/EULAR antiphospholipid syndrome classification …
Catastrophic antiphospholipid syndrome (CAPS) is a rare and life-threatening condition
characterized by the persistence of antiphospholipid antibodies and occurrence of multiple …
characterized by the persistence of antiphospholipid antibodies and occurrence of multiple …
Cardiovascular risk assessment in patients with antiphospholipid syndrome: a cross-sectional performance analysis of nine clinical risk prediction tools
GC Drosos, G Konstantonis, PP Sfikakis… - RMD open, 2023 - rmdopen.bmj.com
Objectives This study aimed to assess the performance of cardiovascular risk (CVR)
prediction models reported by European Alliance of Associations for Rheumatology and …
prediction models reported by European Alliance of Associations for Rheumatology and …
Low recurrent thrombosis rates in single positive antiphospholipid syndrome regardless of type of anticoagulation
BR Bakow, L Yanek, MA Crowther, S Chaturvedi - Thrombosis research, 2024 - Elsevier
Thrombotic antiphospholipid syndrome (TAPS) is characterized by thrombosis and
persistently positive tests for antiphospholipid antibodies or lupus anticoagulant (LAC) …
persistently positive tests for antiphospholipid antibodies or lupus anticoagulant (LAC) …
Classification criteria for the antiphospholipid syndrome: not the same as diagnostic criteria for antiphospholipid syndrome
The latest consensus “guidelines” outlining revised Classification Criteria for
antiphospholipid syndrome (APS) has just been published. 1 The aim of this publication was …
antiphospholipid syndrome (APS) has just been published. 1 The aim of this publication was …
Antiphospholipid syndrome pathogenesis in 2023: an update of new mechanisms or just a reconsideration of the old ones?
E Raschi, MO Borghi, F Tedesco, PL Meroni - Rheumatology, 2024 - academic.oup.com
Antibodies against phospholipid (aPL)-binding proteins, in particular, beta 2 glycoprotein I
(β2GPI), are diagnostic/classification and pathogenic antibodies in antiphospholipid …
(β2GPI), are diagnostic/classification and pathogenic antibodies in antiphospholipid …
New advances in genomics and epigenetics in antiphospholipid syndrome
C López-Pedrera, T Cerdó, EC Jury… - …, 2024 - academic.oup.com
APS patients exhibit a wide clinical heterogeneity in terms of the disease's origin and
progression. This diversity can be attributed to consistent aPL profiles and other genetic and …
progression. This diversity can be attributed to consistent aPL profiles and other genetic and …