The role of the gut microbiota in multiple sclerosis

J Correale, R Hohlfeld, SE Baranzini - Nature Reviews Neurology, 2022 - nature.com
During the past decade, research has revealed that the vast community of micro-organisms
that inhabit the gut—known as the gut microbiota—is intricately linked to human health and …

[HTML][HTML] Immunomodulation in the treatment of periodontitis: Progress and perspectives

B Yang, X Pang, Z Li, Z Chen, Y Wang - Frontiers in immunology, 2021 - frontiersin.org
Periodontitis is one of the most common dental diseases. Compared with healthy
periodontal tissues, the immune microenvironment plays the key role in periodontitis by …

Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer

L Derosa, B Routy, AM Thomas, V Iebba, G Zalcman… - Nature medicine, 2022 - nature.com
Aside from PD-L1 expression, biomarkers of response to immune checkpoint inhibitors (ICIs)
in non-small-cell lung cancer (NSCLC) are needed. In a previous retrospective analysis, we …

Next-generation probiotics–do they open new therapeutic strategies for cancer patients?

K Kaźmierczak-Siedlecka, K Skonieczna-Żydecka… - Gut …, 2022 - Taylor & Francis
Gut microbiota and its association with cancer development/treatment has been intensively
studied during the past several years. Currently, there is a growing interest toward next …

[HTML][HTML] The anti-inflammatory effects of Akkermansia muciniphila and its derivates in HFD/CCL4-induced murine model of liver injury

SKA Raftar, F Ashrafian, S Abdollahiyan, A Yadegar… - Scientific Reports, 2022 - nature.com
Inflammation plays a critical role in the promotion of hepatocyte damage and liver fibrosis. In
recent years the protective role of Akkermansia muciniphila, a next-generation beneficial …

[HTML][HTML] Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut …

H Jian, Y Liu, X Wang, X Dong, X Zou - International Journal of Molecular …, 2023 - mdpi.com
Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

[HTML][HTML] Modulation of bone remodeling by the gut microbiota: a new therapy for osteoporosis

Z Lyu, Y Hu, Y Guo, D Liu - Bone research, 2023 - nature.com
The gut microbiota (GM) plays a crucial role in maintaining the overall health and well-being
of the host. Recent studies have demonstrated that the GM may significantly influence bone …

The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential

R Xu, Y Zhang, S Chen, Y Zeng, X Fu… - Critical reviews in …, 2023 - Taylor & Francis
The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

[HTML][HTML] The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation

J Ouyang, J Lin, S Isnard, B Fombuena… - Frontiers in …, 2020 - frontiersin.org
Gut dysbiosis, namely dysregulation of the intestinal microbiota, and increased gut
permeability lead to enhanced inflammation and are commonly seen in chronic conditions …

[HTML][HTML] Gut microbiota and host metabolism: from proof of concept to therapeutic intervention

PD Cani, E Moens de Hase, M Van Hul - Microorganisms, 2021 - mdpi.com
The field of the gut microbiota is still a relatively young science area, yet many studies have
already highlighted the translational potential of microbiome research in the context of …