Physiological and regulatory convergence between osmotic and nutrient stress responses in microbes
Bacterial cells are regularly confronted with simultaneous changes in environmental nutrient
supply and osmolarity. Despite the importance of osmolarity and osmoregulation in bacterial …
supply and osmolarity. Despite the importance of osmolarity and osmoregulation in bacterial …
Trehalose and bacterial virulence
M Vanaporn, RW Titball - Virulence, 2020 - Taylor & Francis
Trehalose is a disaccharide of two D-glucose molecules linked by a glycosidic linkage,
which plays both structural and functional roles in bacteria. Trehalose can be synthesized …
which plays both structural and functional roles in bacteria. Trehalose can be synthesized …
Effects of NaCl Concentrations on Growth Patterns, Phenotypes Associated With Virulence, and Energy Metabolism in Escherichia coli BW25113
F Li, XS Xiong, YY Yang, JJ Wang, MM Wang… - Frontiers in …, 2021 - frontiersin.org
According to the sit-and-wait hypothesis, long-term environmental survival is positively
correlated with increased bacterial pathogenicity because high durability reduces the …
correlated with increased bacterial pathogenicity because high durability reduces the …
Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment
S Monem, B Furmanek-Blaszk, A Łupkowska… - International Journal of …, 2020 - mdpi.com
Acinetobacter baumannii is considered one of the most persistent pathogens responsible for
nosocomial infections. Due to the emergence of multidrug resistant strains, as well as high …
nosocomial infections. Due to the emergence of multidrug resistant strains, as well as high …
Unraveling the Molecular Mechanisms of Trehalose-Mediated Protection and Stabilization of Escherichia coli Lipid Membrane during Desiccation
A Maiti, S Daschakraborty - The Journal of Physical Chemistry B, 2023 - ACS Publications
Trehalose, a disaccharide renowned for its ability to stabilize biomolecular architectures
under strenuous conditions, finds extensive use in the cryopreservation of probiotics. A …
under strenuous conditions, finds extensive use in the cryopreservation of probiotics. A …
Mechanism of validamycin A inhibiting DON biosynthesis and synergizing with DMI fungicides against Fusarium graminearum
C Bian, Y Duan, Q Xiu, J Wang, X Tao… - Molecular Plant …, 2021 - Wiley Online Library
Deoxynivalenol (DON) is a vital virulence factor of Fusarium graminearum, which causes
Fusarium head blight (FHB). We recently found that validamycin A (VMA), an …
Fusarium head blight (FHB). We recently found that validamycin A (VMA), an …
New insight into the mechanisms protecting bacteria during desiccation
E Laskowska, D Kuczyńska-Wiśnik - Current genetics, 2020 - Springer
Desiccation is a common stress that bacteria face in the natural environment, and thus, they
have developed a variety of protective mechanisms to mitigate the damage caused by water …
have developed a variety of protective mechanisms to mitigate the damage caused by water …
Intracellular Protective Functions and Therapeutical Potential of Trehalose
D Kuczyńska-Wiśnik, K Stojowska-Swędrzyńska… - Molecules, 2024 - mdpi.com
Trehalose is a naturally occurring, non-reducing saccharide widely distributed in nature.
Over the years, research on trehalose has revealed that this initially thought simple storage …
Over the years, research on trehalose has revealed that this initially thought simple storage …
[HTML][HTML] Protein aggregation and glycation in Escherichia coli exposed to desiccation-rehydration stress
A Łupkowska, S Monem, J Dębski… - Microbiological …, 2023 - Elsevier
In natural environments, bacteria often enter a state of anhydrobiosis due to water loss.
Multiple studies have demonstrated that desiccation may lead to protein aggregation and …
Multiple studies have demonstrated that desiccation may lead to protein aggregation and …
Liquid–Liquid Phase Separation and protective protein aggregates in bacteria
D Kuczyńska-Wiśnik, K Stojowska-Swędrzyńska… - Molecules, 2023 - mdpi.com
Liquid–liquid phase separation (LLPS) and the formation of membraneless organelles
(MLOs) contribute to the spatiotemporal organization of various physiological processes in …
(MLOs) contribute to the spatiotemporal organization of various physiological processes in …