The biology of mitochondrial uncoupling proteins
S Rousset, MC Alves-Guerra, J Mozo, B Miroux… - Diabetes, 2004 - Am Diabetes Assoc
Uncoupling proteins (UCPs) are mitochondrial transporters present in the inner membrane
of mitochondria. They are found in all mammals and in plants. They belong to the family of …
of mitochondria. They are found in all mammals and in plants. They belong to the family of …
Animal models of multiple sclerosis—potentials and limitations
E Mix, H Meyer-Rienecker, HP Hartung… - Progress in neurobiology, 2010 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is still the most widely accepted animal
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …
model of multiple sclerosis (MS). Different types of EAE have been developed in order to …
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis
HH Hofstetter, SM Ibrahim, D Koczan, N Kruse… - Cellular …, 2005 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is widely regarded as an animal model
of the human disease multiple sclerosis. A multitude of studies has investigated the …
of the human disease multiple sclerosis. A multitude of studies has investigated the …
Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model
EC Johnson, L Jia, WO Cepurna… - … & visual science, 2007 - iovs.arvojournals.org
purpose. In glaucoma, the optic nerve head (ONH) is the likely site of initial injury and
elevated intraocular pressure (IOP) is the best-known risk factor. This study determines …
elevated intraocular pressure (IOP) is the best-known risk factor. This study determines …
Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice
G van Loo, R De Lorenzi, H Schmidt, M Huth… - Nature …, 2006 - nature.com
Activation of transcription factor NF-κB in the central nervous system (CNS) has been linked
to autoimmune demyelinating disease; however, it remains unclear whether its function is …
to autoimmune demyelinating disease; however, it remains unclear whether its function is …
Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity
M Kunz, SM Ibrahim - Mediators of inflammation, 2009 - Wiley Online Library
The precise pathomechanisms of human autoimmune diseases are still poorly understood.
However, a deepened understanding of these is urgently needed to improve disease …
However, a deepened understanding of these is urgently needed to improve disease …
Respiration uncoupling and metabolism in the control of energy expenditure
D Ricquier - Proceedings of the Nutrition Society, 2005 - cambridge.org
Metabolic energy expenditure negatively regulates energy balance. Metabolic and catabolic
pathways contribute to energy expenditure. Catabolic pathways split C-containing …
pathways contribute to energy expenditure. Catabolic pathways split C-containing …
Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease
A Kalyvas, S David - Neuron, 2004 - cell.com
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) that results in motor and sensory deficits. Although MS and its animal model …
system (CNS) that results in motor and sensory deficits. Although MS and its animal model …
Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing–remitting …
S Rasmussen, Y Wang, P Kivisäkk, RT Bronson… - Brain, 2007 - academic.oup.com
The purpose of this study was to examine the influence of the “good-old-days” bias on
symptom reporting following mild traumatic brain injury (MTBI). The MTBI sample consisted …
symptom reporting following mild traumatic brain injury (MTBI). The MTBI sample consisted …
Neuroprotective Effects of β-caryophyllene against dopaminergic neuron injury in a murine model of Parkinson's disease induced by MPTP
JM Viveros-Paredes, RE González-Castañeda… - Pharmaceuticals, 2017 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative disorders and is
characterized by the loss of dopaminergic neurons in the substantia nigra (SN). Although the …
characterized by the loss of dopaminergic neurons in the substantia nigra (SN). Although the …