Pathogenesis of multiple sclerosis: an update on immunology
B Hemmer, S Cepok, S Nessler… - Current opinion in …, 2002 - journals.lww.com
Multiple sclerosis is characterized by demyelination and chronic inflammation of the central
nervous system. Extensive studies in the animal model experimental autoimmune …
nervous system. Extensive studies in the animal model experimental autoimmune …
β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway
Abstract β-Caryophyllene (BCP), a natural bicyclic sesquiterpene present in several
essential oils, displays analgesic and anti-inflammatory properties in vitro and in vivo …
essential oils, displays analgesic and anti-inflammatory properties in vitro and in vivo …
New roles of carboxypeptidase E in endocrine and neural function and cancer
NX Cawley, WC Wetsel, SRK Murthy, JJ Park… - Endocrine …, 2012 - academic.oup.com
Carboxypeptidase E (CPE) or carboxypeptidase H was first discovered in 1982 as an
enkephalin-convertase that cleaved a C-terminal basic residue from enkephalin precursors …
enkephalin-convertase that cleaved a C-terminal basic residue from enkephalin precursors …
The genetics of multiple sclerosis: review of current and emerging candidates
Multiple sclerosis (MS) is a complex disease in which environmental, genetic, and
epigenetic factors determine the risk of developing the disease. The human leukocyte …
epigenetic factors determine the risk of developing the disease. The human leukocyte …
Connexin43, the major gap junction protein of astrocytes, is down‐regulated in inflamed white matter in an animal model of multiple sclerosis
E Brand‐Schieber, P Werner… - Journal of …, 2005 - Wiley Online Library
Both multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), its
animal model, involve inflammatory attack on central nervous system (CNS) white matter …
animal model, involve inflammatory attack on central nervous system (CNS) white matter …
cDNA microarray analysis in multiple sclerosis lesions: detection of genes associated with disease activity
MP Mycko, R Papoian, U Boschert, CS Raine… - Brain, 2003 - academic.oup.com
Abstract cDNA microarray analysis of the regions of pathologically proven different activity of
multiple sclerosis lesions was performed. Major differences in gene expression (DGE) …
multiple sclerosis lesions was performed. Major differences in gene expression (DGE) …
Transcriptional analysis of targets in multiple sclerosis
L Steinman, S Zamvil - Nature Reviews Immunology, 2003 - nature.com
Large-scale analyses of messenger RNA transcripts and autoantibody responses, taken
from the actual sites of disease, provide us with an unprecedented view of the complexity of …
from the actual sites of disease, provide us with an unprecedented view of the complexity of …
[HTML][HTML] β-Caryophyllene (BCP) ameliorates MPP+ induced cytotoxicity
G Wang, W Ma, J Du - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Parkinson's disease (PD) is one of the most common neurodegenerative diseases resulting
from the continuous death of dopaminergic neurons in substantia nigra. MPP+ (1-methyl-4 …
from the continuous death of dopaminergic neurons in substantia nigra. MPP+ (1-methyl-4 …
Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis
G Opdenakker, I Nelissen, J Van Damme - The Lancet Neurology, 2003 - thelancet.com
Multiple sclerosis (MS) is a demyelinating disease of the CNS of unknown cause.
Pathogenetic mechanisms, such as chemotaxis, subsequent activation of autoreactive …
Pathogenetic mechanisms, such as chemotaxis, subsequent activation of autoreactive …
Gene expression analysis suggests that 1,25-dihydroxyvitamin D3 reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosis
KM Spach, LB Pedersen, FE Nashold… - Physiological …, 2004 - journals.physiology.org
Multiple sclerosis (MS) is a debilitating autoimmune disease of the central nervous system
(CNS) that develops in genetically susceptible individuals who are exposed to undefined …
(CNS) that develops in genetically susceptible individuals who are exposed to undefined …