mRNA expression profile reveals differentially expressed genes in splenocytes of experimental autoimmune encephalomyelitis model
A Mehmood, S Song, X Du, H Yan… - International journal …, 2023 - Wiley Online Library
Experimental autoimmune encephalomyelitis (EAE) is a mouse model that can be used to
investigate aetiology, pathogenesis, and treatment approaches for multiple sclerosis (MS). A …
investigate aetiology, pathogenesis, and treatment approaches for multiple sclerosis (MS). A …
Regulation of gene expression in experimental autoimmune encephalomyelitis indicates early neuronal dysfunction
Multiple sclerosis is an inflammatory, demyelinating disease of the CNS. Whereas
oligodendrocytes have been considered the primary neural cell type most affected, recent …
oligodendrocytes have been considered the primary neural cell type most affected, recent …
Plasma biomarkers discriminate clinical forms of multiple sclerosis
M Tejera-Alhambra, A Casrouge, C de Andrés… - PLoS …, 2015 - journals.plos.org
Multiple sclerosis, the most common cause of neurological disability in young population
after trauma, represents a significant public health burden. Current challenges associated …
after trauma, represents a significant public health burden. Current challenges associated …
Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies
Despite recent advances in the diagnosis and treatment of multiple sclerosis, we still lack a
consensus regarding the causes, pathogenesis, and mechanisms of disease progression …
consensus regarding the causes, pathogenesis, and mechanisms of disease progression …
The role of kinin B1 and B2 receptors in the persistent pain induced by experimental autoimmune encephalomyelitis (EAE) in mice: evidence for the involvement of …
RC Dutra, AF Bento, DFP Leite, MN Manjavachi… - Neurobiology of …, 2013 - Elsevier
Multiple sclerosis (MS) is a progressive, demyelinating inflammatory disease of the human
central nervous system (CNS). While the primary symptoms of MS affect motor function, it is …
central nervous system (CNS). While the primary symptoms of MS affect motor function, it is …
Mast cells: new targets for multiple sclerosis therapy?
Growing evidence suggests that mast cells (MCs) play a crucial role in the inflammatory
process and the subsequent demyelination observed in patients suffering from multiple …
process and the subsequent demyelination observed in patients suffering from multiple …
Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissue
RJ Clements, J McDonough, EJ Freeman - Experimental Brain Research, 2008 - Springer
Parvalbumin (PV) and calretinin (CR) are calcium binding proteins (CBP's) expressed in
discrete GABAergic interneuron populations in the human cortex. CBP's are known to buffer …
discrete GABAergic interneuron populations in the human cortex. CBP's are known to buffer …
Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis
S Vogler, J Pahnke, S Rousset, D Ricquier… - The American journal of …, 2006 - Elsevier
Uncoupling protein 2 (UCP2) is a member of the mitochondrial transporter superfamily that
is expressed in many tissues, including immune cells. UCP2 prevents oxidative stress by …
is expressed in many tissues, including immune cells. UCP2 prevents oxidative stress by …
Overexpression of glial cell line-derived neurotrophic factor induces genes regulating migration and differentiation of neuronal progenitor cells
J Pahnke, E Mix, R Knoblich, J Müller… - Experimental cell …, 2004 - Elsevier
The glial cell line-derived neurotrophic factor (GDNF) is involved in the development and
maintenance of neural tissues. Mutations in components of its signaling pathway lead to …
maintenance of neural tissues. Mutations in components of its signaling pathway lead to …
Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant
S Stosic-Grujicic, Z Ramic… - Clinical & …, 2004 - academic.oup.com
Experimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple
sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE …
sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE …