[HTML][HTML] Multidisciplinary clinical guidance on trastuzumab deruxtecan (T-DXd)–related interstitial lung disease/pneumonitis—focus on proactive monitoring, diagnosis …

SM Swain, M Nishino, LH Lancaster, BT Li… - Cancer treatment …, 2022 - Elsevier
Abstract Trastuzumab deruxtecan (T-DXd; DS-8201) is an antibody-drug conjugate targeting
human epidermal growth factor receptor 2. Interstitial lung disease (ILD)/pneumonitis is an …

Nuclear and radiological emergencies: biological effects, countermeasures and biodosimetry

E Obrador, R Salvador-Palmer, JI Villaescusa… - Antioxidants, 2022 - mdpi.com
Atomic and radiological crises can be caused by accidents, military activities, terrorist
assaults involving atomic installations, the explosion of nuclear devices, or the utilization of …

A human lung alveolus-on-a-chip model of acute radiation-induced lung injury

Q Dasgupta, A Jiang, AM Wen, RJ Mannix… - Nature …, 2023 - nature.com
Acute exposure to high-dose gamma radiation due to radiological disasters or cancer
radiotherapy can result in radiation-induced lung injury (RILI), characterized by acute …

[HTML][HTML] Exploration of radiation-induced lung injury, from mechanism to treatment: a narrative review

Y Yan, J Fu, RO Kowalchuk, CM Wright… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Methods PubMed was used to collect articles about RILI from 1995 to 2021. The papers
included clinical trials, reviews, as well as systematic reviews and meta-analyses. Based on …

[HTML][HTML] Crossed pathways for radiation-induced and immunotherapy-related lung injury

Z Zhang, J Zhou, V Verma, X Liu, M Wu, J Yu… - Frontiers in …, 2021 - frontiersin.org
Radiation-induced lung injury (RILI) is a form of radiation damage to normal lung tissue
caused by radiotherapy (RT) for thoracic cancers, which is most commonly comprised of …

[HTML][HTML] Inhaled curcumin mesoporous polydopamine nanoparticles against radiation pneumonitis

T Chen, B Zhuang, Y Huang, Y Liu, B Yuan… - … Pharmaceutica Sinica B, 2022 - Elsevier
Radiation therapy is an effective method to kill cancer cells and shrink tumors using high-
energy X-ray or γ-ray. Radiation pneumonitis (RP) is one of the most serious complications …

Quercetin-3-Rutinoside alleviates radiation-induced lung inflammation and fibrosis via regulation of NF-κB/TGF-β1 signaling

S Verma, A Dutta, A Dahiya, N Kalra - Phytomedicine, 2022 - Elsevier
Background Radiation exposure to lungs during nuclear catastrophes or radiotherapy poses
long-term side effects and can induce pulmonary injury sufficient for causing death. The …

Re-Du-Ning injection ameliorates radiation-induced pneumonitis and fibrosis by inhibiting AIM2 inflammasome and epithelial-mesenchymal transition.

C Yang, C Song, Y Wang, W Zhou, W Zheng, H Zhou… - Phytomedicine, 2022 - Elsevier
Background Radiation-induced lung injury (RILI) is a common side effect in chest
radiotherapy patients, and there is no good medicine to treat it. Re-Du-Ning (RDN) injection …

Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury

X Rao, D Zhou, H Deng, Y Chen, J Wang, X Zhou… - Respiratory …, 2023 - Springer
Background Radiation-induced lung injury (RILI) is the most common and serious
complication of chest radiotherapy. However, reported radioprotective agents usually lead to …

Radiation-induced lung injury—current perspectives and management

MS Rahi, J Parekh, P Pednekar, G Parmar… - Clinics and …, 2021 - mdpi.com
Radiotherapy plays an important role in the treatment of localized primary malignancies
involving the chest wall or intrathoracic malignancies. Secondary effects of radiotherapy on …