Endogenous circadian rhythms are thought to modulate responses to external factors, but
mechanisms that confer time-of-day differences in organismal responses to environmental …

The brain clock that drives circadian rhythms of locomotor activity relies on a multi-oscillator
neuronal network. In addition to synchronizing the clock with day-night cycles, light also …

Despite being pervasive, the control of programmed grooming is poorly understood. We
addressed this gap by developing a high-throughput platform that allows long-term detection …

Mitochondrial encephalomyopathies (ME) are complex, incurable diseases characterized by
severe bioenergetic distress that can affect the function of all major organ systems but is …

Magnesium and its related preparations are already in medical use and have recognized
therapeutic effects on sleep disorders. However, its underlying molecular mechanisms …

Under standard laboratory conditions, Drosophila melanogaster, a crepuscular insect,
displays a bimodal activity pattern principally regulated by the endogenous circadian clock …

Magnesium and its related preparations are already in medical use and have recognized
pharmacological effects on neurologic disorders. However, little is known about the role of …

Relying on the rapid development of computer technology, machine learning is increasingly
being applied to studies of animal behaviors. Video tracking enables observation of …

Sleep is a universal behavioral and physiological state observed in most carefully studied
animals characterized by a period of reduced motor activity and elevated thresholds of …

Highlights The Drosophila BBB displays a circadian rhythm of permeability Cyclic efflux
driven by a clock in the BBB underlies the permeability rhythm Circadian control is non-cell …