Alzheimer's disease (AD) is the most common form of dementia worldwide, with a complex,
poorly understood pathogenesis. Cerebral atrophy, amyloid-β (Aβ) plaques, and …

Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Significance: Alzheimer disease (AD) is an all-too-common condition in the aging
population. However, aging does not automatically equal neurodegeneration and memory …

Background Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and
is characterized by progressive memory loss and cognitive impairment. Our understanding …

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …

Cell type-specific transcriptional differences between brain tissues from donors with
Alzheimer's disease (AD) and unaffected controls have been well documented, but few …

Alzheimer's disease (AD) is determined by various pathophysiological mechanisms starting
10–25 years before the onset of clinical symptoms. As multiple functionally interconnected …

We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting
of endoplasmic reticulum stress as a potential emerging therapeutic strategy against …

Amyloid fibril formation plays a central role in the pathogenesis of a number of
neurodegenerative diseases, including Alzheimer and Parkinson diseases. Transient …

Alzheimer's disease (AD) is a multivariate and diversified disease and affects the most
sensitive areas of the brain, the cerebral cortex, and the hippocampus. AD is a progressive …