Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …

Aging is a multi-faceted process caused by the accumulation of cellular damage over time,
associated with a gradual reduction of physiological activities in cells and organs. This …

Sarcopenic obesity, which refers to concurrent sarcopenia and obesity, is characterized by
decreased muscle mass, strength, and performance along with abnormally excessive fat …

Introduction and aim Myostatin and follistatin are the main hormones for regulating muscle
mass, and previous research suggests they are modulated by resistance training. We …

Sarcopenia and obese sarcopenia are increasingly prevalent chronic diseases with
multifactorial pathogenesis, and no approved therapeutic drug to date. In the established …

An association between the loss of skeletal muscle mass and obesity in the geriatric
population has been identified as a disease known as sarcopenic obesity. Therefore …

Dementia is a detrimental neuropathologic condition with considerable physical, mental,
social, and financial impact on patients and society. Patients with metabolic syndrome …

Myostatin negatively regulates skeletal muscle growth and appears upregulated in human
obesity and associated with insulin resistance. However, observations are confounded by …

Epigenetic changes contribute to the profound alteration in the transcriptional program
associated with the onset and progression of muscle wasting in several pathological …

Musculoskeletal research should synergistically investigate bone and muscle to inform
approaches for maintaining mobility and to avoid bone fractures. The relationship between …