Compelling epidemiologic and molecular data indicate that genes play a primary role in
determining who is at risk for developing multiple sclerosis (MS), how the disease …

Abstract The interleukin (IL)-1 system plays a major role in immune responses and
inflammation. The IL-1 system components include IL-1α, IL-1β, IL-1 receptor type 1 and IL-1 …

Evidence is mounting that genetic variation influences not only susceptibility to multiple
sclerosis (MS), but also its course and severity. Identification of disease modifying genes …

Reactive oxygen species (ROS) play an important role in various events underlying multiple
sclerosis pathology. In the initial phase of lesion formation, ROS are known to mediate the …

The aim of our investigation was to analyze the pattern of interleukin-1 (IL-1) family
compounds: IL-1 beta, IL-1 receptor accessory protein (Acp), IL-1 receptor antagonist (IL …

Objectives: In order to elucidate the genetic background to EOP it is useful to investigate
associations with genetic polymorphisms of immune response genes, whose products play …

Multiple sclerosis and anesthetic implications : Current Opinion in Anesthesiology Multiple
sclerosis and anesthetic implications : Current Opinion in Anesthesiology Log in or Register …

Objective: The pathogenesis of vulvar vestibulitis syndrome remains unknown but may be
related to a localized chronic inflammation. The relation between this syndrome and a …

Nerve injury and the consequent release of interleukins (ILs) are processes implicated in
pain transmission. To study the potential role of IL-1 in the pathogenesis of allodynia and …

We studied genetic polymorphisms in the promoter region (position-511) and exon 5
(position+ 3953) of the interleukin (IL)-1β gene in 122 Japanese patients with Parkinson's …