Multiple sclerosis (MS) is a demyelinating autoimmune disease of the central nervous
system caused by an interplay of environmental and genetic factors. The only genetic region …

The efficacy of glatiramer acetate in multiple sclerosis (MS) is thought to involve the
production of Th2 regulatory lymphocytes that secrete anti-inflammatory cytokines; however …

We investigated PvuII and XbaI polymorphism in the estrogen receptor gene (ERG) and HLA-
DRB1* 1501 positivity in 116 conventional multiple sclerosis (MS) patients and 101 healthy …

Alterations in glutamate transport and group I metabotropic glutamate receptors in the rat brain
during acute phase of experimen Page 1 Folia Neuropathologica 2009; 47/4 329 Alterations in …

Background Dysregulated levels of interleukin-1 (IL-1) were observed in patients with
multiple sclerosis (MS). Previous studies have provided conflicting evidence implicating the …

The autoimmune nature of multiple sclerosis introduces cytokine genes as logical
candidates for the loci determining susceptibility to the disease, and/or influencing disease …

In this explorative study, interleukin-1 (IL-1) receptor antagonist (IL-1RA; polymorphism of
variable number of tandem repeats: VNTR), IL-1α (− 889), IL-1β (− 511) and IL-1β (+ 3953) …

Multiple sclerosis (MS) is a multi-factorial autoimmune disease of the central nervous
system. The exact etiology of MS is still unknown. Due to the important roles that cytokines …

Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the
CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised …

In the present study, we have investigated the association of specific polymorphisms of the
interleukin (IL)-1β and IL-1 receptor antagonist (ra) gene with both the susceptibility to and …